Affinity DataKi: 0.00100nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.00140nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.00150nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.00200nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Binding affinity to human Bradykinin receptor B1 over-expressed in transgenic rats was determined by ex vivo receptor occupancy assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0130nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0150nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0180nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Binding affinity to human Bradykinin receptor B1 over-expressed in transgenic rats was determined by ex vivo receptor occupancy assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to rhesus monkey Bradykinin receptor B1More data for this Ligand-Target Pair
Affinity DataKi: 0.0200nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to human Bradykinin receptor B1 over-expressed in transgenic rats was determined by ex vivo rec...More data for this Ligand-Target Pair
Affinity DataKi: 0.0300nMAssay Description:Binding affinity to human Bradykinin receptor B1 over-expressed in transgenic rats was determined by ex vivo receptor occupancy assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0330nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 0.0340nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Binding affinity of the [35S]- radiolabelled compound to rabbit Bradykinin receptor B1More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 0.0520nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Binding affinity to human Bradykinin receptor B1 over-expressed in transgenic rats was determined by ex vivo receptor occupancy assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Binding affinity to human Bradykinin receptor B1 over-expressed in transgenic rats was determined by ex vivo receptor occupancy assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.0800nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.0850nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0870nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.0960nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.125nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Binding affinity to human MCH1R expressed in CHO cells by scintillation counting per mg of proteinMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.230nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition constant against human ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Binding affinity to human bradikinin B1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibitory potency against human thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Binding affinity against thrombin in human plasmaMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibitory constant against thrombin (IIa) More data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Tsukuba Research Institute
Curated by ChEMBL
Tsukuba Research Institute
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Displacement of [35S] 4-(1-(3,4-difluorophenyl)-2-(ethyl(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)amino)-2-oxoethyl)-3-oxopip...More data for this Ligand-Target Pair