TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 expressed in HEK293 cell membranes incubated for 40 or 90 mins by liquid scintillat...More data for this Ligand-Target Pair
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.130nMAssay Description:Inhibition of Trypanosoma brucei alternative oxidase expressed in Escherichia coli FN102 using ubiquinol-1 as substrate preincubated for 2 mins follo...More data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.180nMAssay Description:Displacement of [3H]-flumazenil from human GABAA alpha1beta3gamma2 expressed in HEK293 cell membranes measured after 2 hrs by liquid scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of 3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-flumazenil from human GABAA alpha3beta3gamma2 expressed in Ltk cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]-flumazenil from human GABAA alpha1beta3gamma2 expressed in Ltk cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.230nMAssay Description:Displacement of [3H]-flumazenil from human GABAA alpha5beta3gamma2 expressed in Ltk cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to GABA-A alpha2 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.309nMAssay Description:Binding affinity to GABA-A alpha2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.398nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.410nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha1beta3gamma2 expressed in HEK293 cell membranes incubated for 40 or 90 mins by liquid scintillat...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-Ro15-1788 from human GABAA alpha3beta3gamma2 expressed in HEK293 cell membranes incubated for 40 or 90 mins by liquid scintillat...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of 3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of 3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Binding affinity to GABA-A alpha2 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.610nMAssay Description:Binding affinity to GABA-A alpha3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of 3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.631nMAssay Description:Displacement of 3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.660nMAssay Description:Binding affinity to GABA-A alpha5 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.670nMAssay Description:Displacement of [3H]-flumazenil from human GABAA alpha3beta3gamma2 expressed in Ltk cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.730nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.770nMAssay Description:Binding affinity to GABA-A alpha3 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.790nMAssay Description:Displacement of [3H]-flumazenil from human GABAA alpha1beta3gamma2 expressed in Ltk cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of 3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]5-HT from human cloned 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]WAY-100635 from human cloned 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]5HT from human recombinant 5HT1D receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]WAY100635 from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.794nMAssay Description:Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human N-terminal His6-tagged BRD4 BD1-BD2 (57 to 550 residues) expressed in EScherichia coli BL21(DE3) after 1 hr by Alexa-647-conjugat...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.830nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.850nMAssay Description:Binding affinity to GABA-A alpha2 (unknown origin)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
University Of Sussex
Curated by ChEMBL
University Of Sussex
Curated by ChEMBL
Affinity DataKi: 0.880nMAssay Description:Binding affinity to GABA-A alpha1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: >1nMAssay Description:Agonist activity at rat 5HT1A receptorMore data for this Ligand-Target Pair