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Found 981 with Last Name = 'wu' and Initial = 'jj'
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10173(lysine sulfonamide analogue 34 | pyridin-4-ylmethy...)
Affinity DataKi:  0.0200nM IC50:  0.390nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10177((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.330nM IC50:  0.330nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10170((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.340nM IC50:  0.240nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10172(lysine sulfonamide analogue 33 | pyridin-3-ylmethy...)
Affinity DataKi:  0.360nM IC50:  0.480nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10171(lysine sulfonamide analogue 32 | pyridin-2-ylmethy...)
Affinity DataKi:  0.400nM IC50:  0.120nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10165((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.400nM IC50:  0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10175((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.400nM IC50:  0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10169((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.400nM IC50:  0.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10162((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.440nM IC50:  0.460nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10155((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.450nM IC50:  0.430nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10179((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.450nM IC50:  0.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10161((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.470nM IC50:  0.430nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10176((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.470nM IC50:  0.530nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10178((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.480nM IC50:  0.560nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10166((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.5nM IC50:  0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10168((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.5nM IC50:  0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10157(lysine sulfonamide analogue 18 | tert-butyl N-[(1S...)
Affinity DataKi:  0.5nM IC50:  0.400nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10159((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.550nM IC50:  0.510nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10163((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.550nM IC50:  0.680nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10153((2S)-2-amino-N-[(5R)-5-[(4-aminobenzene)(2-methylp...)
Affinity DataKi:  0.560nM IC50:  0.5nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10158((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.580nM IC50:  0.440nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10174((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.580nM IC50:  0.630nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10160((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.600nM IC50:  0.520nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10164((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.660nM IC50:  0.650nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10167((2S)-N-[(5R)-5-[(4-aminobenzene)(2-methylpropyl)su...)
Affinity DataKi:  0.700nM IC50:  0.900nMAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615622(US20230271949, Example 413)
Affinity DataKi:  14.1nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615623(US20230271949, Example 414)
Affinity DataKi:  15.6nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615625(US20230271949, Example 416)
Affinity DataKi:  29.3nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615593(US20230271949, Example 384)
Affinity DataKi:  68.3nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615617(US20230271949, Example 408)
Affinity DataKi:  68.4nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615626(US20230271949, Example 417)
Affinity DataKi:  69.2nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615595(US20230271949, Example 386)
Affinity DataKi:  69.9nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615407(US20230271949, Example 198 | US20230271949, Exampl...)
Affinity DataKi:  70.3nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615294(US20230271949, Example 85)
Affinity DataKi:  71.7nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615551(US20230271949, Example 342)
Affinity DataKi:  72.2nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615620(US20230271949, Example 411)
Affinity DataKi:  72.6nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615438(US20230271949, Example 229)
Affinity DataKi:  75.9nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615454(US20230271949, Example 245)
Affinity DataKi:  82.3nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615416(US20230271949, Example 207)
Affinity DataKi:  82.4nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615594(US20230271949, Example 385)
Affinity DataKi:  82.7nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615406(US20230271949, Example 197)
Affinity DataKi:  84nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615405(US20230271949, Example 196)
Affinity DataKi:  87.9nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615549(US20230271949, Example 340)
Affinity DataKi:  88.5nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615412(US20230271949, Example 203)
Affinity DataKi:  90.3nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615550(US20230271949, Example 341)
Affinity DataKi:  95.5nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615616(US20230271949, Example 407)
Affinity DataKi:  110nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615453(US20230271949, Example 244)
Affinity DataKi:  110nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615624(US20230271949, Example 415)
Affinity DataKi:  117nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615101(US20230271949, Example 2)
Affinity DataKi:  165nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Ascletis Bioscience

US Patent
LigandPNGBDBM615596(US20230271949, Example 387)
Affinity DataKi:  205nMAssay Description:Tag-Lite Binding Assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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