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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM615407
Substrate
n/a
Meas. Tech.
Tag-Lite Binding Assay
Ki
70.3±n/a nM
Citation
 Liang, B; Yang, Y; Wang, P; Yang, B; Lai, Y; Wu, JJ GLP-1R MODULATING COMPOUNDS US Patent  US20230271949 Publication Date 8/31/2023 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM615407
Synonyms:
US20230271949, Example 198 | US20230271949, Example 391
Type:
Small organic molecule
Emp. Form.:
C37H35ClN8O3
Mol. Mass.:
675.179
SMILES:
Cc1n[nH]c2ccc(cc12)C(=O)Nc1ccc2n(C[C@@H]3CCO3)c(CN3CCC(=CC3)c3cccc(OCc4ccc(Cl)cn4)n3)nc2c1 |r,c:31|
Structure:
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