Found 224 with Last Name = 'xue' and Initial = 't' TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 93nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 190nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Binding affinity to MDM2 in human MCF7 cells assessed as inhibition of MDM2-p53 interactionMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Science And Peking Union Medical College
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Binding affinity to MDM2 (1 to 118) (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
Affinity DataIC50: 2.36nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.82nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 6nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 6nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 7nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 7nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 8nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 8nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
Affinity DataIC50: 8.27nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 9nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 9nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
Affinity DataIC50: 9.39nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
Affinity DataIC50: 9.83nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Chinese Academy Of Medical Sciences & Peking Union Medical College
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 5 mins followed by NADPH addition and measured after 20 mi...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 12nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:(Promega), the inhibitory effect of the compounds of the present invention on the enzymatic activity of TGFβR1 was determined, and the steps wer...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 12nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 13nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 13nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 15nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 15nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 17nMT: 2°CAssay Description:The kit is based on ELISA. 10 μl sample/well, 15 μl PARP enzyme/well and PARP cocktail 25 μl/well with a total volume of 50 μl/we...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Chengdu Diao Pharmaceutical Group
US Patent
Chengdu Diao Pharmaceutical Group
US Patent
Affinity DataIC50: 17nMT: 2°CAssay Description:PARP-1 can catalyze the NAD-dependent addition of poly (ADP-ribose) to adjacent nuclear proteins such as histone. The activity of PARP was determined...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human factor 10a using N-Z-D-Arg-Gly-Arg-pNA, S-2765 chromogenic substrateMore data for this Ligand-Target Pair
