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Found 19 with Last Name = 'yang' and Initial = 'wb'
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11234((2S)-N-(2-chloro-4-nitrophenyl)-2-{[4-(dimethylami...)
Affinity DataKi:  30nM ΔG°:  -42.9kJ/mole IC50:  60nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11240(Anilide Inhibitor 4k | N-[(benzyloxy)carbonyl]-L-v...)
Affinity DataKi:  1.51E+3nM ΔG°:  -33.2kJ/mole IC50:  6.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11239((2S)-N-[(1S)-1-{[(1S,2S)-1-{[(1S)-1-[(2-chloro-4-n...)
Affinity DataKi:  1.61E+3nM ΔG°:  -33.1kJ/mole IC50:  5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11236((2S)-N-[(1S)-1-[(2-chloro-4-nitrophenyl)carbamoyl]...)
Affinity DataKi:  2.29E+3nM ΔG°:  -32.2kJ/mole IC50:  5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11237((2S)-N-[(1S)-1-{[(1S)-1-[(2-chloro-4-nitrophenyl)c...)
Affinity DataKi:  2.90E+3nM ΔG°:  -31.6kJ/mole IC50:  7.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11241((2S)-N,N'-bis[(1S)-1-[(2-chloro-4-nitrophenyl)carb...)
Affinity DataKi:  3.10E+3nM ΔG°:  -31.4kJ/mole IC50:  4.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11238((2S)-N-[(1S)-1-{[(1S)-1-[(2-chloro-4-nitrophenyl)c...)
Affinity DataKi:  4.30E+3nM ΔG°:  -30.6kJ/mole IC50:  5.00E+3nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50099009((3S,4S,5R)-2-Aminomethyl-5-hydroxymethyl-pyrrolidi...)
Affinity DataIC50:  53nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50099009((3S,4S,5R)-2-Aminomethyl-5-hydroxymethyl-pyrrolidi...)
Affinity DataIC50:  670nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50:  750nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50241865(2,5-dideoxy-2,5-imino-D-altritol | 2R,5R-dihydroxy...)
Affinity DataIC50:  1.00E+3nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204611(CHEMBL1289018 | D-15)
Affinity DataIC50:  9.50E+3nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11235(Anilide Inhibitor 3d | tert-butyl N-[(1S)-1-{[(1S)...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204610(CHEMBL3908900)
Affinity DataIC50:  1.06E+4nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204609(CHEMBL3985941)
Affinity DataIC50:  1.40E+4nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204613(CHEMBL3929052)
Affinity DataIC50:  2.21E+4nMpH: 7.0Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 7 after 15 mins by fluoresc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204610(CHEMBL3908900)
Affinity DataIC50:  3.42E+4nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
National Taiwan University

LigandPNGBDBM11242(5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...)
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-galactosidase A(Homo sapiens (Human))
National Cheng Kung University

Curated by ChEMBL
LigandPNGBDBM50204609(CHEMBL3985941)
Affinity DataIC50:  2.66E+5nMpH: 4.6Assay Description:Inhibition of human recombinant lysosomal alpha GAL-A using 4-methylberiilyl alpha-D-galactopyranoside as substrate at pH 4.6 after 10 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed