Affinity DataKi: 0.470nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0140nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0220nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0240nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0240nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0270nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0310nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0470nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0480nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0480nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0570nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0570nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0590nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0590nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin B receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0620nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.0650nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nM EC50: 0.310nMAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.660nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.740nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
TargetEndothelin-1 receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibitory activity against [125I]-ET-1 binding to human endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nM EC50: 2.40nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair