Compile Data Set for Download or QSAR
maximum 50k data
Found 983 with Last Name = 'zack' and Initial = 'd'
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17744(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...)
Affinity DataIC50:  0.600nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17744(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[3-(4-me...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17734(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM50374627(CHEMBL270692)
Affinity DataIC50:  1nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17730(2,6-dimethylphenyl N-[(2,5-dimethoxyphenyl)methyl]...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17728(2,6-dimethylphenyl N-[4-fluoro-2-(propan-2-yloxy)p...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17726(2,6-dimethylphenyl N-(2-methoxyphenyl)-N-(2-{[4-(4...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17735(2,6-dimethylphenyl N-(2-{[3,5-dimethoxy-4-(4-methy...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17736(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17738(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17739(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17740(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(4-me...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17741(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(morp...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17742(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17743(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17745(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17730(2,6-dimethylphenyl N-[(2,5-dimethoxyphenyl)methyl]...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17735(2,6-dimethylphenyl N-(2-{[3,5-dimethoxy-4-(4-methy...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17740(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(4-me...)
Affinity DataIC50:  1nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637195(US20230382904, Compound 115)
Affinity DataIC50:  1.30nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637184(US20230382904, Compound 104)
Affinity DataIC50:  1.70nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637157(US20230382904, Compound 77)
Affinity DataIC50:  1.80nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17743(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17741(2,6-dimethylphenyl N-[2-({3,5-dimethoxy-4-[2-(morp...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17736(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17729(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17734(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-(2-{[...)
Affinity DataIC50:  2nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

LigandPNGBDBM17746(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637196(US20230382904, Compound 116)
Affinity DataIC50:  2.20nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637109(US20230382904, Compound 29 | US20230382904, Compou...)
Affinity DataIC50:  2.30nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  2.40nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637109(US20230382904, Compound 29 | US20230382904, Compou...)
Affinity DataIC50:  2.80nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637203(US20230382904, Compound 123)
Affinity DataIC50:  2.90nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637244(US20230382904, Compound 159)
Affinity DataIC50:  2.90nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17727(2,6-dimethylphenyl N-(4-methoxyphenyl)-N-(2-{[4-(4...)
Affinity DataIC50:  3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637168(US20230382904, Compound 88)
Affinity DataIC50:  3.20nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637192(2-Amino-N-[(2S)-butan-2-yl]-6-(5-{[(1S)-1-(4-fluor...)
Affinity DataIC50:  3.20nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637171(US20230382904, Compound 91)
Affinity DataIC50:  3.30nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637108(US20230382904, Compound 28 | US20230382904, Compou...)
Affinity DataIC50:  3.40nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637247(US20230382904, Compound 162)
Affinity DataIC50:  3.5nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637169(US20230382904, Compound 89)
Affinity DataIC50:  3.70nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17737(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17738(2,6-dimethylphenyl N-(2,4-dimethoxyphenyl)-N-[2-({...)
Affinity DataIC50:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen

LigandPNGBDBM17726(2,6-dimethylphenyl N-(2-methoxyphenyl)-N-(2-{[4-(4...)
Affinity DataIC50:  4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50374627(CHEMBL270692)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637188(US20230382904, Compound 108)
Affinity DataIC50:  4nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637237(US20230382904, Compound 152)
Affinity DataIC50:  4.15nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637218(US20230382904, Compound 138)
Affinity DataIC50:  4.20nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein delta homolog 1(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM637240(US20230382904, Compound 155)
Affinity DataIC50:  4.30nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 983 total ) | Next | Last >>
Jump to: