TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human 20s constitutive proteasome beta5 chymotrypsin-like activity using Suc-LLVY-AMC as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of DGAT1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of DGAT1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human 20s immunoproteasome beta5i activity using Suc-LLVY-AMC as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human 20s constitutive proteasome beta5 chymotrypsin-like activity using Suc-LLVY-AMC as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of DGAT1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human 20s constitutive proteasome beta5 chymotrypsin-like activity using Suc-LLVY-AMC as substrate preincubated for 15 mins followed by...More data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of DGAT1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human 20s immunoproteasome beta5i activity using Suc-LLVY-AMC as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human 20s immunoproteasome beta5i activity using Suc-LLVY-AMC as substrate preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetA5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436(Homo sapiens (Human))
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Hangzhou Institute Of Innovative Medicine
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human 20S proteasome preincubated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of DGAT1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPAMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of DGAT1 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair