TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: <1nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 7nM ΔG°: -42.6kJ/mole EC50: 90nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to human ERbeta LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Binding affinity to human ERbeta LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 26nM ΔG°: -39.7kJ/mole EC50: 6.00E+3nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 39nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Binding affinity to human ERbeta LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 47nM ΔG°: -38.3kJ/mole EC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Affinity DataKi: 48nM ΔG°: -38.3kJ/mole EC50: 600nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity to human ERbeta LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 51nM ΔG°: -38.1kJ/molepH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 57nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity to human ERbeta LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 68nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 71nM ΔG°: -37.4kJ/mole EC50: 40nMpH: 7.5 T: 2°CAssay Description:Relative binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer, and purified full-length human ...More data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Binding affinity to human ERbeta LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 71nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Binding affinity to human ERbeta LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 79nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 81nMAssay Description:Binding affinity to human ER-alpha ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 82nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 84nMAssay Description:Binding affinity to human ERalpha LBD assessed as inhibition constant measured after 2 hrs by microplate readerMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Inhibition of FAM-Bid binding to human MCL1 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: 87nMAssay Description:Binding affinity to human ER-beta ligand binding domain after 2 hrs by competitive fluorometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 88nMAssay Description:Binding affinity to human ERalpha LBD after 2 hrs in absence of light by competitive fluorometric binding assayMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Wuhan University School Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Inhibition of FAM-Bid binding to human BCL2 expressed in Escherichia coli BL21 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair