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Found 32 with Last Name = 'di paola' and Initial = 'r'
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50236217(CHEMBL4061448)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM81395(APO-866)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50236220(CHEMBL4074848)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of NAMPT in human Jurkat T cells assessed as reduction in NAD levelsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236219(CHEMBL4066091)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236221(CHEMBL4078882)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236223(CHEMBL4083606)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236222(CHEMBL4101611)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236224(CHEMBL4088492)
Affinity DataIC50:  32nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236216(CHEMBL4064240)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236218(CHEMBL4094769)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50549365(CHEMBL3403742)
Affinity DataIC50:  228nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNicotinamide phosphoribosyltransferase(Mus musculus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50236215(CHEMBL4087071)
Affinity DataIC50:  269nMAssay Description:Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50450630(CHEMBL101896)
Affinity DataIC50:  300nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50549358(CHEMBL4753023)
Affinity DataIC50:  361nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50450629(CHEMBL4177187)
Affinity DataIC50:  500nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50450626(CHEMBL4162723)
Affinity DataIC50:  600nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549357(CHEMBL4794288)
Affinity DataIC50:  781nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549360(CHEMBL4780000)
Affinity DataIC50:  802nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549363(CHEMBL4751678)
Affinity DataIC50:  807nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549362(CHEMBL4761656)
Affinity DataIC50:  851nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549356(CHEMBL4799904)
Affinity DataIC50:  866nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549359(CHEMBL4750981)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549361(CHEMBL4742227)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50549364(CHEMBL4742960)
Affinity DataIC50:  1.79E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetStromal interaction molecule 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50450629(CHEMBL4177187)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of STIM1/STIM2/Orai1 (unknown origin) expressed in mouse BV2 cells assessed as reduction of store-operated calcium entry at 100 uM preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50450627(CHEMBL4162062)
Affinity DataIC50:  3.10E+3nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50018011(Aubagio | CHEBI:68540 | HMR-1726 | TERIFLUNOMIDE)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of STIM1/Orai1 (unknown origin) expressed in HEK293 cells assessed as reduction in tBHQ-induced calcium responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50450628(CHEMBL4172741)
Affinity DataIC50:  4.40E+3nMAssay Description:Modulation of TRPC1/TRPC3/STIM1/Orai1 in HEK cells assessed as induction of store-operated calcium entry by measuring residual activity preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromal interaction molecule 1(Homo sapiens)
Universit£

Curated by ChEMBL
LigandPNGBDBM50450626(CHEMBL4162723)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of STIM1/STIM2/Orai1 (unknown origin) expressed in mouse BV2 cells assessed as induction of store-operated calcium entry by measuring resi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed