Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50400035,50400036,50400037,50400038,50400039,50400035,50400036,50400037,50400038,50400039   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400035(CHEMBL2177735 | US9169259, I-84)
Affinity DataIC50: 15.6nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400035(CHEMBL2177735 | US9169259, I-84)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400036(CHEMBL2177734 | US9169259, I-68)
Affinity DataIC50: 24.7nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400036(CHEMBL2177734 | US9169259, I-68)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400037(CHEMBL2177733 | US9169259, I-5)
Affinity DataIC50: 127nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400037(CHEMBL2177733 | US9169259, I-5)
Affinity DataIC50: 127nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400038(CHEMBL2177732 | US9169259, I-4)
Affinity DataIC50: 351nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400038(CHEMBL2177732 | US9169259, I-4)
Affinity DataIC50: 351nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

TargetTyrosine-protein kinase SYK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400039(CHEMBL2177731 | US9169259, I-3)
Affinity DataIC50: 406nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400039(CHEMBL2177731 | US9169259, I-3)
Affinity DataIC50: 406nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent