Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  2.70nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  2.70nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  2.70nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194226(US9200006, 4)
Affinity DataKi:  2.70nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  300nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  300nMAssay Description:The enzyme is commercially available human cathepsin L (for example Calbiochem). The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194226(US9200006, 4)
Affinity DataKi:  300nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  300nMAssay Description:The enzyme is commercially available human cathepsin L. The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assay buffer is 100 mM sodium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  1.45E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  1.45E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123100(US10723709, Example 4 | US11312693, Example 4 | US...)
Affinity DataKi:  1.45E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194226(US9200006, 4)
Affinity DataKi:  1.45E+4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent