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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191384((5R),(6E)-6-(5,6-dihydro-8H-imidazo[2,1-c][1,4]thi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191384((5R),(6E)-6-(5,6-dihydro-8H-imidazo[2,1-c][1,4]thi...)
Affinity DataIC50:  420nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191384((5R),(6E)-6-(5,6-dihydro-8H-imidazo[2,1-c][1,4]thi...)
Affinity DataIC50:  730nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetImipenem-hydrolyzing beta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50191384((5R),(6E)-6-(5,6-dihydro-8H-imidazo[2,1-c][1,4]thi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Enterobacter cloacae Imi1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed