Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 23 hits in this display
IC50: 2.20E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) expressed in human HEK-Freestyle cells using Boc-Lys(Ac) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
IC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 15 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
IC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate incubated for 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 15 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-(+)-mephenytoin as substrate incubated for 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate incubated for 15 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
IC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate incubated for 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate incubated for 15 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Kd: >5.00E+3nMAssay Description:Displacement of [3H]4-DAMP from human recombinant M4 receptor incubated for 1 hr by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
Kd: >5.00E+3nMAssay Description:Displacement of [3H]4-DAMP from human recombinant M3 receptor incubated for 1 hr by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
Kd: >5.00E+3nMAssay Description:Displacement of [3H]AF-DX384 from human recombinant M2 receptor incubated for 1 hr by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
Kd: >5.00E+3nMAssay Description:Displacement of [3H]pirenzapine from human recombinant M1 receptor incubated for 1 hr by radiometric scintillation counting analysisMore data for this Ligand-Target Pair