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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Acetylcholine receptor subunit alpha/beta/delta/gamma
(Torpedo californica)
University Of W£Rzburg
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
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Affinity Data
Ki: 550nM
Assay Description:
Displacement of (+/-)-[3H]epibatidine from muscle type nAChR of Torpedo californica in hepes buffer
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
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Affinity Data
Ki: 3.16E+3nM
Assay Description:
Displacement of [3H]methyllycaconitine from alpha7 nAChR in tsA201 cells co-expressed with Ric3
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.98E+3nM
Assay Description:
Displacement of [3H]methyllycaconitine from human alpha-7 in tsA201 cells coexpressed with 5HT3A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H]GR65630 from human 5HT3A receptor in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.00E+4nM
Assay Description:
Antagonist activity at human alpha-7 nAChR in tsA201 cells coexpressed with Ric3 by FMP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycine receptor subunit alpha-1
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Antagonist activity at human glycine alpha-1 receptor in HEK293 cells by FMP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
University Of Copenhagen
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Antagonist activity at human 5HT3A receptor expressed in HEK293 cells by FMP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
University Of W£Rzburg
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
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Affinity Data
EC50: 2.29E+3nM
Assay Description:
Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in hepes buffer
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human))
University Of W£Rzburg
Curated by
ChEMBL
Ligand
BDBM50220045
(CHEMBL206666 | [(20-{[dimethyl(prop-2-en-1-yl)azan...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 110nM
Assay Description:
Inhibition of [3H]NMS dissociation from muscarinic M2 receptor in Na,K,Pi buffer
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI