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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Affinity Data
Ki: 8.20nM
Assay Description:
Displacement of [3H]-TAK-875 from human recombinant full-length GPR40 expressed in human HEK293 cell membrane incubated for 2 hrs by solid scintillat...
More data for this Ligand-Target Pair
Target Info
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Article
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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B.MOAD
DrugBank
antibodypedia
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Article
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Target
Free fatty acid receptor 1
(Mus musculus)
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Affinity Data
EC50: 1.20nM
Assay Description:
Agonist activity at Prolink-tagged mouse GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arresti...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Article
PubMed
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Target
Melanocortin receptor 4
(Rattus norvegicus)
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Affinity Data
EC50: 1.70nM
Assay Description:
Agonist activity at Prolink-tagged rat GPR40 fused with EA-tagged beta-arrestin expressed in human U2OS cells assessed as induction of beta-arrestin ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Ligand Info
PC cid
PC sid
In Depth
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Article
PubMed
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Target
Peroxisome proliferator-activated receptor gamma/Retinoic acid receptor RXR-alpha
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human CMV-fused PPARgamma LBD/RXRalpha (unknown origin) expressed in African green monkey CV1 cells transfected with luciferase p...
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Target Info
PDB
Reactome pathway
KEGG
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antibodypedia
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Ligand Info
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PC sid
In Depth
Details
Article
PubMed
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Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Copy InChI
Affinity Data
Kd: 3.5nM
Assay Description:
Displacement of [3H]-(S)-2-(6-((2',6'-dimethyl-4'-(3-(methylsulfonyl)propoxy)biphenyl-3-yl)methoxy)-2,3-dihydrobenzofuran-3-yl)acetic acid from human...
More data for this Ligand-Target Pair
Target Info
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PC sid
In Depth
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Article
PubMed
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Target
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human Gal4-fused PPARalpha LBD expressed in African green monkey CV1 cells cotransfected with pRL-SV40 plasmid measured after 24 ...
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Target Info
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Article
PubMed
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Target
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
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Affinity Data
EC50: >1.00E+4nM
Assay Description:
Agonist activity at human Gal4-fused PPARdelta LBD expressed in African green monkey CV1 cells cotransfected with pRL-SV40 plasmid measured after 24 ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.90nM
Assay Description:
Agonist activity at human recombinant full-length Prolink-tagged GPR40 fused with EA-tagged beta-arrestin expressed in human HEK293 cells assessed as...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
Copy SMILES
Copy InChI
Affinity Data
EC50: 8nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in intracellular calcium level measu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Free fatty acid receptor 1
(Homo sapiens (Human))
Lilly Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50563863
(CHEMBL4787498)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.10nM
Assay Description:
Agonist activity at human recombinant full length GPR40 overexpressed in human HEK293 cells assessed as increase in inositol phosphate accumulation i...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI