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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 12 hits in this display   

TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  400nMAssay Description:Inhibitory concentration against Cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  400nMAssay Description:Protein phosphatases were purchased from Upstate Biotechnology (Lake Placid, NY).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  500nMAssay Description:Inhibitory concentration against Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of Lck (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of protein tyrosine phosphatase N1 (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of protein tyrosine phosphatase N13 (unknown origin) phosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50099692(CHEMBL51314 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed