Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 18 hits in this display
Ki: 1.10E+3nMAssay Description:Competitive inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: 1.80E+3nMAssay Description:Biphasic inhibition of CYP2C8 in human liver microsomes assessed as montelukast 36-hydroxylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: 6.00E+3nMAssay Description:Competitive inhibition of CYP2C8 in human liver microsomes assessed as rosiglitazone demethylation after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: >3.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: >3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: >3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: >3.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using (S)-Mephenytoin as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: >3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ki: >3.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
IC50: 3nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 receptor expressed in human HEK293 cells by scintillation counter in presence of 0.5% bovine serum albuminMore data for this Ligand-Target Pair
IC50: 8nMAssay Description:Displacement of [3H]-PGD2 from human CRTH2 receptor expressed in human HEK293 cells by scintillation counter in presence of 50% human plasmaMore data for this Ligand-Target Pair
IC50: 5.40E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes assessed as paclitaxel 6-hydroxylation after 5 to 30 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair