Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

LigandBDBM50502344(Talinolol)Copy SMILESCopy InChI

Affinity DataKi:  240nMAssay Description:Binding affinity to beta1 adrenergic receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails ArticlePubMed
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TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

LigandBDBM50502344(Talinolol)Copy SMILESCopy InChI

Affinity DataKi:  900nMAssay Description:Binding affinity to beta2 adrenergic receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Goethe-University Of Frankfurt

Curated by ChEMBL

LigandBDBM50502344(Talinolol)Copy SMILESCopy InChI

Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant human full length soluble epoxide hydrolase (1 to 555 residues) expressed in Escherichia coli BL21(DE3) using non-fluoresce...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDB

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI