SMILES String Search

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 940 hits in this display

Receptor-type tyrosine-protein kinase FLT3 [D835Y](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 0.00200nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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3D Structure (crystal)

Receptor-type tyrosine-protein kinase FLT3 [D835Y](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 0.00200nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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3D Structure (crystal)

Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 0.236nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 0.236nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: <0.510nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

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Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 0.623nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 0.623nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Cyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 0.900nMAssay Description:Inhibition of FLT3 ITD mutant (unknown orgin) by ADP-glo kinase assayMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 1.10nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 1.10nMAssay Description:Inhibition of FLT3-ITD autophosphorylation in human MV4-11 cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 1.10nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells preincubated for 2 hrs followed by FLT3 ligand addition and measured after 15 minsMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 1.10nMAssay Description:Inhibition of human partial length FLT3 ITD mutant expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Dimer of Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 1.93nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2nMAssay Description:Inhibition of FLT3 autophosphorylation in human AML cells isolated from relapsed acute myeloid leukemia patient by Western blottingMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2nMAssay Description:Competitive inhibition of FLT3 ITD mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2.06nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2.06nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2.60nMAssay Description:Inhibition of FLT3-ITD mutant (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 3nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.10nMAssay Description:Inhibition of wild type FLT3 (unknown origin) by ADP-glo kinase assayMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.20nMAssay Description:Inhibition of human FLT3 ITD mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.20nMAssay Description:Inhibition of wild type FLT3 (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells measured after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.20nMAssay Description:Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assayMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.20nMAssay Description:Inhibition of wild-type human partial length FLT3 (V592 to Y969 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.20nMAssay Description:Inhibition of FLT3 (unknown origin) (592 to 969 residues)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.80nMAssay Description:Inhibition of FLT3 (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair

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Dimer of Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: <5nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 6.5nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 7.40nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 10nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 10nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) ITD mutant expressed in Sf9 insect cells using poly (Ala,Glu,L...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 12nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 13.8nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 13.8nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 15.9nMAssay Description:In the experiments of in vitro enzymatic activity, the IC50 values of Compound 33, Compound 30, Compound 14, Compound 20, Compound 22, Compound 23, C...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 20nMAssay Description:Antagonism of isoprenaline-induced relaxation of guinea pig tracheal chains, contracted with carbacholMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 20nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-tagged FLT3 ITD mutant (571 to 993 residues) expressed in Sf9 cells using Tyr2 peptide as substra...More data for this Ligand-Target Pair

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Tyrosine-protein kinase Blk(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 20.7nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Tyrosine-protein kinase Blk(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 26nMAssay Description:Inhibition of recombinant human FLT3 expressed in insect Sf21 cells preincubated for 15 mins followed by poly(Glu:Tyr) substrate addition for 30 mins...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 26nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human wild-type FLT3 (564 to end residues) expressed in baculovirus infected sf21 cells using Abltide...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 30nMAssay Description:Inhibition of human HL60 cells-derived His-tagged FLT3 (564 to 993 residues) expressed in baculovirus infected sf9 cells using poly (4:1 Glu, Tyr) as...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 30nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IM...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 36nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant wild type human FLT3 (R571 to S993 residues) expressed in Sf9 insect cells using poly (Ala,Glu,Ly...More data for this Ligand-Target Pair

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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 37.8nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 37.8nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 39nMAssay Description:Inhibition of FLT3 (unknown origin) using FAM-EPLYWSFPA as substrate preincubated for 60 mins followed by substrate addition by microfluidics assay i...More data for this Ligand-Target Pair

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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 42nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair

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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 42nMAssay Description:Inhibition of recombinant human 3C cleavage site/N-terminal GST-His6 fused PDGFR alpha C-terminal fragment (Q551 to L1089 residues) harboring V561D m...More data for this Ligand-Target Pair

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Tyrosine-protein kinase Lck(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 57.8nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Tyrosine-protein kinase Lck(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 57.8nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 69nMAssay Description:Inhibition of wild type GST-tagged FLT3 kinase domain (Y567 to S993) (unknown origin) expressed in baculovirus infected insect Sf9 cells using Her2 p...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 69nMAssay Description:Inhibition of wild type GST tagged FLT3 kinase (567 to 993) (unknown origin) transfected in insect sf9 cells after 4 hrs by wallac counting analysisMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 69nMAssay Description:Inhibition of wild type FLT3More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 72nMAssay Description:FLT3 is a receptor tyrosine kinase involved in survival and proliferation of leukemic cells. Constitutively activating FLT3 mutations has been found ...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 93nMAssay Description:Competitive inhibition of FLT3 D835Y mutant (unknown origin) in presence of ATPMore data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 116nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 116nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 120nMAssay Description:Inhibition of human FLT3 using 10 uM ATPMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 120nMAssay Description:Inhibition of FLT3 kinase (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 136nMAssay Description:Inhibition of N-terminal GST/His6-fused recombinant human FLT3 (R571 to S993 residues) D835Y mutant expressed in Sf9 insect cells using poly (Ala,Glu...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 137nMAssay Description:Inhibition of human FLT3 D835Y mutant EAIYAAPFAKKK peptide as substrate in presence of 33P-gamma ATP by hotspot kinase assayMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 137nMAssay Description:Inhibition of human FLT D835Y mutant using 10 uM ATPMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 170nMAssay Description:Inhibition of wildtype FLT3 (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 258nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) using Poly (Glu,Tyr) 4:1 as substrate incubated for 1 hr in presence of ATP by ELISAMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 430nMAssay Description:Inhibition of recombinant GST-tagged VEGFR2 kinase domain (V789 to V1356) (unknown origin) expressed in insect Sf9 cells using polyGlu4:Tyr peptide a...More data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 430nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 520nMAssay Description:Inhibition of FLT3 ITD/D835Y double mutant (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 625nMAssay Description:Inhibition of FLT3 ITD/F691L double mutant (unknown origin) expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 1.33E+3nMAssay Description:Inhibition of FLT3 D835Y (unknown origin) using TAMRA-Src-tide as substrate measured after 1 hr in presence of ATP at its Km concentration by IMAP-FP...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 1.51E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) obtained from human WIL2 cellsMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 4.90E+3nMAssay Description:Inhibition of human VEGFR3 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: >1.00E+4nMAssay Description:Inhibition of human VEGFR2 using poly[Glu:Tyr] (4:1) substrate and [gamma-33P]-ATP by radiometric biochemical kinase assayMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: >1.00E+4nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: >1.00E+4nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: >1.00E+4nMAssay Description:Inhibition of recombinant GST-tagged Aurora-A kinase domain (S123 to S401) (unknown origin) expressed in insect Sf9 cells using tetra(LRRASLG) peptid...More data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: >1.00E+4nMAssay Description:Inhibition of recombinant GST tagged Aurora A kinase (123 to 401) (unknown origin) transfected in insect sf9 cells after 90 mins by wallac counting a...More data for this Ligand-Target Pair

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Cyclin-dependent kinase 2(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: >2.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair

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Cyclin-A1/Cyclin-dependent kinase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2.00E+4nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair

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SRSF protein kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2.17E+4nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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SRSF protein kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 2.17E+4nMAssay Description:Table 3 and 4: The HotSpot kinase profiling and screening assays were carried out using the method of Anastassiadis et al., Nat. Biotechnol. (2011) V...More data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding affinity to FLT4More data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMKK2More data for this Ligand-Target Pair

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Inhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to IKK-alphaMore data for this Ligand-Target Pair

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SRSF protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SRPK3More data for this Ligand-Target Pair

KEGG
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Cyclin-dependent kinase 15(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PFTAIRE2More data for this Ligand-Target Pair

KEGG
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Ribosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA5(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

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Ephrin type-A receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA1More data for this Ligand-Target Pair

PDB Reactome pathway
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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 410nMAssay Description:Binding affinity to MLCKMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Death-associated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DAPK1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Hormonally up-regulated neu tumor-associated kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to HUNKMore data for this Ligand-Target Pair

KEGG
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to FLT3More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Mitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ZAKMore data for this Ligand-Target Pair

PDB NCI pathway KEGG
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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MYLKMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 35(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to STK35More data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase ULK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ULK1More data for this Ligand-Target Pair

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Serine/threonine-protein kinase Chk1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CHEK1More data for this Ligand-Target Pair

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Serine/threonine-protein kinase TAO1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TAOK1More data for this Ligand-Target Pair

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Cyclin-dependent kinase 11A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDC2L2More data for this Ligand-Target Pair

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ALK tyrosine kinase receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ALKMore data for this Ligand-Target Pair

PDB KEGG
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Myosin-IIIb(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MYO3BMore data for this Ligand-Target Pair

PDB KEGG
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Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TYK2(JH2domain-pseudokinase)More data for this Ligand-Target Pair

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Myotonin-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DMPKMore data for this Ligand-Target Pair

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AP2-associated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AAK1More data for this Ligand-Target Pair

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Rho-associated protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ROCK2More data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding affinity to FLT4More data for this Ligand-Target Pair

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Serine/threonine-protein kinase DCLK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DCAMKL2More data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase MRCK gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DMPK2More data for this Ligand-Target Pair

KEGG
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cGMP-dependent protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKG1More data for this Ligand-Target Pair

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Macrophage-stimulating protein receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MST1RMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase BRSK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BRSK1More data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase TNNI3K(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TNNI3KMore data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase ULK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ULK2More data for this Ligand-Target Pair

PDB KEGG
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MAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MARK3More data for this Ligand-Target Pair

PDB MMDB KEGG
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Protein kinase C eta type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKCHMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Misshapen-like kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MINKMore data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to IRAK3More data for this Ligand-Target Pair

PDB NCI pathway
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Protein kinase C alpha type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA2(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

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SRSF protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SRPK2More data for this Ligand-Target Pair

PDB MMDB KEGG
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Mitogen-activated protein kinase kinase kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAP3K4More data for this Ligand-Target Pair

KEGG
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Ribosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA6(Kin.Dom.2-C-terminal)More data for this Ligand-Target Pair

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Ephrin type-A receptor 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA6More data for this Ligand-Target Pair

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Serine/threonine-protein kinase D2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKD2More data for this Ligand-Target Pair

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Insulin receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to INSRMore data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to JAK1 JH2 domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK2BMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to FLT3 catalytic domain by KinomeScan kinase binding assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA3(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

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Serine/threonine-protein kinase 17A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DRAK1More data for this Ligand-Target Pair

PDB KEGG
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Calcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK2GMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK2AMore data for this Ligand-Target Pair

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Aurora kinase B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AURKBMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA1(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(H1047L) kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1-phosphorylated kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RPS6KA5(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair

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Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LRRK2(G2019S) kinase domainMore data for this Ligand-Target Pair

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MAP/microtubule affinity-regulating kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MARK3 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(E542K) kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(Y253F)-phosphorylated kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.60E+3nMAssay Description:Binding constant for ABL1(T315I)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair

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Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TYK2(JH2domain-pseudokinase) kinase domainMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.10nMAssay Description:Binding constant for FLT3(D835Y) kinase domainMore data for this Ligand-Target Pair

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Insulin receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for INSR kinase domainMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.60nMAssay Description:Binding constant for KIT(A829P) kinase domainMore data for this Ligand-Target Pair

PDB Reactome pathway
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(C420R) kinase domainMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3nMAssay Description:Binding constant for RET(M918T) kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(Q252H)-phosphorylated kinase domainMore data for this Ligand-Target Pair

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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(S752-I759del) kinase domainMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(M1043I) kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(E545A) kinase domainMore data for this Ligand-Target Pair

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eIF-2-alpha kinase GCN2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for GCN2(Kin.Dom.2,S808G) kinase domainMore data for this Ligand-Target Pair

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Ephrin type-A receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHA1 kinase domainMore data for this Ligand-Target Pair

PDB Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 8.80nMAssay Description:Binding constant for FLT3(ITD) kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MET kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(H396P)-phosphorylated kinase domainMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding constant for FLT4 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(F317L)-phosphorylated kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(E255K)-phosphorylated kinase domainMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 320nMAssay Description:Binding constant for KIT(D816H) kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAP3K4 kinase domainMore data for this Ligand-Target Pair

KEGG
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Protein kinase C eta type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKCH kinase domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type II subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK2A kinase domainMore data for this Ligand-Target Pair

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AP2-associated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AAK1 kinase domainMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 6nMAssay Description:Binding constant for KIT(V559D,T670I) kinase domainMore data for this Ligand-Target Pair

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Aurora kinase B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AURKB kinase domainMore data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for IRAK3 kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.20nMAssay Description:Binding constant for FLT3(K663Q) kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Hepatocyte growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MET(M1250T) kinase domainMore data for this Ligand-Target Pair

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Myosin-IIIb(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MYO3B kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(G719C) kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair

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Death-associated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DAPK1 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(E545K) kinase domainMore data for this Ligand-Target Pair

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SRSF protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SRPK2 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RSK1(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair

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Myosin light chain kinase, smooth muscle(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MYLK kinase domainMore data for this Ligand-Target Pair

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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(L858R,T790M) kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(F317I)-phosphorylated kinase domainMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.30nMAssay Description:Binding constant for FLT3 kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(T790M) kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1-nonphosphorylated kinase domainMore data for this Ligand-Target Pair

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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(L747-T751del,Sins) kinase domainMore data for this Ligand-Target Pair

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Ephrin type-A receptor 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 9.10E+3nMAssay Description:Binding constant for EPHA6 kinase domainMore data for this Ligand-Target Pair

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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Chk1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CHEK1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(M351T)-phosphorylated kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(I800L) kinase domainMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.70nMAssay Description:Binding constant for FLT3(D835H) kinase domainMore data for this Ligand-Target Pair

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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(E746-A750del) kinase domainMore data for this Ligand-Target Pair

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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(L747-E749del, A750P) kinase domainMore data for this Ligand-Target Pair

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cGMP-dependent protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKG1 kinase domainMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 9.10nMAssay Description:Binding constant for RET(V804M) kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RSK4(Kin.Dom.2-C-terminal) kinase domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMKK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase D2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKD2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 17A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DRAK1 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(L858R) kinase domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK2B kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(F317L)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(F317I)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase TNNI3K(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TNNI3K kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Ribosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RPS6KA4(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(G719S) kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BRAF kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase BRSK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BRSK1 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(Q546K) kinase domainMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 6.30nMAssay Description:Binding constant for KIT(L576P) kinase domainMore data for this Ligand-Target Pair

PDB Reactome pathway
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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 150nMAssay Description:Binding constant for KIT(D816V) kinase domainMore data for this Ligand-Target Pair

PDB Reactome pathway
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Cyclin-dependent kinase 11A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDC2L2 kinase domainMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 13nMAssay Description:Binding constant for RET(V804L) kinase domainMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 36nMAssay Description:Binding constant for KIT(V559D,V654A) kinase domainMore data for this Ligand-Target Pair

PDB Reactome pathway
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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(L861Q) kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(H396P)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair

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Myotonin-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DMPK kinase domainMore data for this Ligand-Target Pair

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Macrophage-stimulating protein receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MST1R kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for JAK1(JH2domain-pseudokinase) kinase domainMore data for this Ligand-Target Pair

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Misshapen-like kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MINK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase MRCK gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DMPK2 kinase domainMore data for this Ligand-Target Pair

KEGG
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Cyclin-dependent kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK4-cyclinD1 kinase domainMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.80nMAssay Description:Binding constant for KIT kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(T315I)-phosphorylated kinase domainMore data for this Ligand-Target Pair

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Rho-associated protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ROCK2 kinase domainMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 5.10nMAssay Description:Binding constant for FLT3(R834Q) kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Inhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for IKK-alpha kinase domainMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FGFR3(G697C) kinase domainMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.80nMAssay Description:Binding affinity to KitMore data for this Ligand-Target Pair

PDB Reactome pathway
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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 11nMAssay Description:Binding affinity to PDGFRalphaMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding affinity to FLT1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Epithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 81nMAssay Description:Binding affinity to DDR1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 87nMAssay Description:Binding affinity to VEGFR2More data for this Ligand-Target Pair

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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.70nMAssay Description:Binding affinity to PDGFRbetaMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 9.90nMAssay Description:Binding affinity to RETMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 12nMAssay Description:Binding affinity to CSF1RMore data for this Ligand-Target Pair

PDB
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to FLT3 catalytic domain expressed in HEK293 cells by competitive binding assayMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Serine/threonine-protein kinase PAK 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PAK6More data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PAK7More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cyclin-dependent kinase 16(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PCTK1More data for this Ligand-Target Pair

PDB
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Cyclin-dependent kinase 17(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PCTK2More data for this Ligand-Target Pair

KEGG
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Cyclin-dependent kinase 18 [3-474](Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PCTK3More data for this Ligand-Target Pair

KEGG
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3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PDPK1More data for this Ligand-Target Pair

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Cyclin-dependent kinase 14(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PFTK1More data for this Ligand-Target Pair

KEGG
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Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PHKG1More data for this Ligand-Target Pair

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Phosphorylase b kinase gamma catalytic chain, liver/testis isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PHKG2More data for this Ligand-Target Pair

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Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK3C2BMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK3C2GMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK3CAMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK3CBMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK3CDMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK3CGMore data for this Ligand-Target Pair

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Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIK4CBMore data for this Ligand-Target Pair

PDB Reactome pathway
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Serine/threonine-protein kinase pim-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIM1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Serine/threonine-protein kinase pim-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIM2More data for this Ligand-Target Pair

PDB MMDB KEGG
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Serine/threonine-protein kinase pim-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIM3More data for this Ligand-Target Pair

KEGG
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Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIP5K1AMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Phosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PIP5K2BMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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cAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PKAC-betaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PKMYT1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Serine/threonine-protein kinase N1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PKN1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase N2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PKN2More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase PLK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PLK1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase PLK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PLK2More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase PLK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PLK3More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PLK4More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Protein kinase C delta type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKCDMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Protein kinase C epsilon type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKCEMore data for this Ligand-Target Pair

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Protein kinase C theta type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKCQMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase D1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKD1More data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase D3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKD3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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cGMP-dependent protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKG2More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Interferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKRMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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cAMP-dependent protein kinase catalytic subunit PRKX(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRKXMore data for this Ligand-Target Pair

Reactome pathway KEGG
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U4/U6 small nuclear ribonucleoprotein Prp4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PRP4More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Protein-tyrosine kinase 2-beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PYK2More data for this Ligand-Target Pair

PDB Reactome pathway
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Serine/threonine-protein kinase SIK3 [59-1321](Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to QSKMore data for this Ligand-Target Pair

PDB KEGG
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RAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RAF1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase RIO1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RIOK1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Serine/threonine-protein kinase RIO2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RIOK2More data for this Ligand-Target Pair

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Serine/threonine-protein kinase RIO3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RIOK3More data for this Ligand-Target Pair

Reactome pathway KEGG
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Receptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RIPK1More data for this Ligand-Target Pair

PDB Reactome pathway
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Receptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RIPK2More data for this Ligand-Target Pair

PDB Reactome pathway
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Receptor-interacting serine/threonine-protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RIPK4More data for this Ligand-Target Pair

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Rho-associated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ROCK1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Proto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ROS1More data for this Ligand-Target Pair

PDB KEGG
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Ribosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA1(Kin.Dom.2-C-terminal)More data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Ribosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA2(Kin.Dom.2-C-terminal)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA4(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA4(Kin.Dom.2-C-terminal)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA5(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to RPS6KA6(Kin.Dom.1-N-terminal)More data for this Ligand-Target Pair

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Ribosomal protein S6 kinase beta-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SBK1More data for this Ligand-Target Pair

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Myosin light chain kinase family member 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SgK085More data for this Ligand-Target Pair

PDB MMDB KEGG
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Uncharacterized serine/threonine-protein kinase SBK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SgK110More data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase SIK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SIKMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SIK2More data for this Ligand-Target Pair

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STE20-like serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SLKMore data for this Ligand-Target Pair

PDB MMDB KEGG
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NUAK family SNF1-like kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SNARKMore data for this Ligand-Target Pair

KEGG
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Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SRCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tyrosine-protein kinase Srms(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SRMSMore data for this Ligand-Target Pair

Reactome pathway KEGG
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SRSF protein kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SRPK1More data for this Ligand-Target Pair

PDB MMDB KEGG
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Serine/threonine-protein kinase 16(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to STK16More data for this Ligand-Target Pair

PDB
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Serine/threonine-protein kinase 33(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to STK33More data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase 36(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to STK36More data for this Ligand-Target Pair

NCI pathway KEGG
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STE20/SPS1-related proline-alanine-rich protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to STK39More data for this Ligand-Target Pair

PDB MMDB KEGG
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Tyrosine-protein kinase SYK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to SYKMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Serine/threonine-protein kinase TAO1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TAO1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Serine/threonine-protein kinase TAO3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TAOK3More data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TBK1More data for this Ligand-Target Pair

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Tyrosine-protein kinase Tec(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TECMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Dual specificity testis-specific protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TESK1More data for this Ligand-Target Pair

Reactome pathway KEGG
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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TGFBR1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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TGF-beta receptor type-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TGFBR2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Angiopoietin-1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TIE2More data for this Ligand-Target Pair

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Serine/threonine-protein kinase tousled-like 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TLK1More data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase tousled-like 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TLK2More data for this Ligand-Target Pair

PDB KEGG
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TRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TNIKMore data for this Ligand-Target Pair

PDB Reactome pathway
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Non-receptor tyrosine-protein kinase TNK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TNK1More data for this Ligand-Target Pair

PDB KEGG
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Poly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TNK2More data for this Ligand-Target Pair

PDB Reactome pathway
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Testis-specific serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TSSK1BMore data for this Ligand-Target Pair

KEGG
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Dual specificity protein kinase TTK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TTKMore data for this Ligand-Target Pair

PDB MMDB KEGG
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Tyrosine-protein kinase TXK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TXKMore data for this Ligand-Target Pair

PDB Reactome pathway
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Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TYK2(JH1domain-catalytic)More data for this Ligand-Target Pair

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Tyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to TYRO3More data for this Ligand-Target Pair

PDB MMDB KEGG
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Serine/threonine-protein kinase ULK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ULK3More data for this Ligand-Target Pair

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Wee1-like protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to WEE1More data for this Ligand-Target Pair

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Wee1-like protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to WEE2More data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase 32B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to YANK2More data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase 32C(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to YANK3More data for this Ligand-Target Pair

KEGG
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Tyrosine-protein kinase Yes(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to YESMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 25(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to YSK1More data for this Ligand-Target Pair

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Tyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ZAP70More data for this Ligand-Target Pair

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NUAK family SNF1-like kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ARK5More data for this Ligand-Target Pair

Reactome pathway KEGG
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Mitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ASK1More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ASK2More data for this Ligand-Target Pair

KEGG
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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AURKAMore data for this Ligand-Target Pair

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Aurora kinase C(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AURKCMore data for this Ligand-Target Pair

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Tyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AXLMore data for this Ligand-Target Pair

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BMP-2-inducible protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BIKEMore data for this Ligand-Target Pair

PDB KEGG
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Tyrosine-protein kinase Blk(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BLKMore data for this Ligand-Target Pair

Reactome pathway KEGG
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Bone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BMPR1AMore data for this Ligand-Target Pair

PDB Reactome pathway
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Bone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BMPR1BMore data for this Ligand-Target Pair

PDB
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Bone morphogenetic protein receptor type-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BMPR2More data for this Ligand-Target Pair

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Cytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BMXMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BRAFMore data for this Ligand-Target Pair

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Protein-tyrosine kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BRKMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BRSK2More data for this Ligand-Target Pair

PDB NCI pathway KEGG
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Tyrosine-protein kinase BTK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to BTKMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK1More data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK1DMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK1GMore data for this Ligand-Target Pair

PDB KEGG
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Calcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK2DMore data for this Ligand-Target Pair

PDB
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Calcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMK4More data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CAMKK1More data for this Ligand-Target Pair

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Cyclin-dependent kinase 11B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDC2L1More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Serine/threonine-protein kinase MARK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MARK1More data for this Ligand-Target Pair

PDB
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Serine/threonine-protein kinase MARK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MARK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway KEGG
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MAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MARK4More data for this Ligand-Target Pair

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Microtubule-associated serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAST1More data for this Ligand-Target Pair

PDB MMDB KEGG
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Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MEK1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Dual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MEK2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Dual specificity mitogen-activated protein kinase kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MEK3More data for this Ligand-Target Pair

Reactome pathway KEGG
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Dual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MEK4More data for this Ligand-Target Pair

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Dual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MEK6More data for this Ligand-Target Pair

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Maternal embryonic leucine zipper kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MELKMore data for this Ligand-Target Pair

PDB KEGG
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Tyrosine-protein kinase Mer(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MERTKMore data for this Ligand-Target Pair

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to METMore data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MKNK1More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Cyclin-dependent kinase 19(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDK11More data for this Ligand-Target Pair

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Cyclin-dependent kinase 2(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDK2More data for this Ligand-Target Pair

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Cyclin-dependent kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDK3More data for this Ligand-Target Pair

PDB KEGG
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Cyclin-dependent kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDK5More data for this Ligand-Target Pair

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Cyclin-dependent kinase 7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDK7More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Cyclin-dependent kinase 8(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDK8More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Cyclin-dependent kinase 9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDK9More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Cyclin-dependent kinase-like 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDKL2More data for this Ligand-Target Pair

PDB
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Cyclin-dependent kinase-like 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDKL3More data for this Ligand-Target Pair

PDB KEGG
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Cyclin-dependent kinase-like 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CDKL5More data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase Chk2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CHEK2More data for this Ligand-Target Pair

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Citron Rho-interacting kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CITMore data for this Ligand-Target Pair

Reactome pathway KEGG
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Dual specificity protein kinase CLK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CLK1More data for this Ligand-Target Pair

PDB MMDB KEGG
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Dual specificity protein kinase CLK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CLK2More data for this Ligand-Target Pair

PDB
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Dual specificity protein kinase CLK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CLK3More data for this Ligand-Target Pair

PDB
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Dual specificity protein kinase CLK4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CLK4More data for this Ligand-Target Pair

PDB MMDB KEGG
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Tyrosine-protein kinase CSK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSKMore data for this Ligand-Target Pair

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Casein kinase I isoform alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK1A1LMore data for this Ligand-Target Pair

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Casein kinase I isoform delta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK1DMore data for this Ligand-Target Pair

PDB Reactome pathway
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Casein kinase I isoform epsilon(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK1EMore data for this Ligand-Target Pair

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Casein kinase I isoform gamma-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK1G1More data for this Ligand-Target Pair

PDB MMDB NCI pathway KEGG
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Casein kinase I isoform gamma-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK1G2More data for this Ligand-Target Pair

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Casein kinase I isoform gamma-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK1G3More data for this Ligand-Target Pair

PDB MMDB NCI pathway KEGG
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Casein kinase II subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK2A1More data for this Ligand-Target Pair

PDB Reactome pathway
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Casein kinase II subunit alpha'(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CSNK2A2More data for this Ligand-Target Pair

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Megakaryocyte-associated tyrosine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to CTKMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Death-associated protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DAPK2More data for this Ligand-Target Pair

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Death-associated protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DAPK3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Serine/threonine-protein kinase DCLK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DCAMKL1More data for this Ligand-Target Pair

PDB MMDB KEGG
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Serine/threonine-protein kinase DCLK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DCAMKL3More data for this Ligand-Target Pair

KEGG
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Protein delta homolog 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DLKMore data for this Ligand-Target Pair

Reactome pathway KEGG
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Serine/threonine-protein kinase 17B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DRAK2More data for this Ligand-Target Pair

PDB
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DYRK1AMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Dual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DYRK1BMore data for this Ligand-Target Pair

PDB
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Dual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to DYRK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EGFRMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Ephrin type-A receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Ephrin type-A receptor 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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Ephrin type-A receptor 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA4More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Ephrin type-A receptor 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA5More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Ephrin type-A receptor 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA7More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
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Ephrin type-A receptor 8(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHA8More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Ephrin type-B receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHB1More data for this Ligand-Target Pair

PDB Reactome pathway
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Ephrin type-B receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHB2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Ephrin type-B receptor 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHB3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Ephrin type-B receptor 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to EPHB4More data for this Ligand-Target Pair

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Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERBB2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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Receptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERBB3More data for this Ligand-Target Pair

PDB MMDB KEGG
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Receptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERBB4More data for this Ligand-Target Pair

PDB MMDB
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Mitogen-activated protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERK1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Mitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Mitogen-activated protein kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERK3More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Mitogen-activated protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERK4More data for this Ligand-Target Pair

Reactome pathway KEGG
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Mitogen-activated protein kinase 7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERK5More data for this Ligand-Target Pair

PDB Reactome pathway
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Serine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ERN1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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Focal adhesion kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FAKMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Fer(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FERMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Fes/Fps(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FESMore data for this Ligand-Target Pair

PDB Reactome pathway
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Fibroblast growth factor receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FGFR1More data for this Ligand-Target Pair

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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FGFR2More data for this Ligand-Target Pair

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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FGFR3More data for this Ligand-Target Pair

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Fibroblast growth factor receptor 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FGFR4More data for this Ligand-Target Pair

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Tyrosine-protein kinase Fgr(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FGRMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Fyn(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to FYNMore data for this Ligand-Target Pair

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Cyclin-G-associated kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to GAKMore data for this Ligand-Target Pair

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Rhodopsin kinase GRK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to GRK1More data for this Ligand-Target Pair

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G protein-coupled receptor kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to GRK4More data for this Ligand-Target Pair

PDB KEGG
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Rhodopsin kinase GRK7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Glycogen synthase kinase-3 alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to GSK3AMore data for this Ligand-Target Pair

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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to GSK3BMore data for this Ligand-Target Pair

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Tyrosine-protein kinase HCK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to HCKMore data for this Ligand-Target Pair

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Homeodomain-interacting protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to HIPK1More data for this Ligand-Target Pair

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Homeodomain-interacting protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to HIPK2More data for this Ligand-Target Pair

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Homeodomain-interacting protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to HIPK3More data for this Ligand-Target Pair

PDB KEGG
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Mitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to HPK1More data for this Ligand-Target Pair

PDB NCI pathway KEGG
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Serine/threonine-protein kinase ICK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ICKMore data for this Ligand-Target Pair

KEGG
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Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to IGF1RMore data for this Ligand-Target Pair

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Inhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to IKK-betaMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to IKK-epsilonMore data for this Ligand-Target Pair

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Insulin receptor-related protein(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to INSRRMore data for this Ligand-Target Pair

PDB KEGG
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Interleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to IRAK1More data for this Ligand-Target Pair

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Tyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ITKMore data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to JH1 catalytic domain JAK1More data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to JH1 catalytic domain JAK2More data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to JH1 catalytic domain of JAK3More data for this Ligand-Target Pair

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Mitogen-activated protein kinase 8(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to JNK1More data for this Ligand-Target Pair

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Mitogen-activated protein kinase 9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to JNK2More data for this Ligand-Target Pair

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Mitogen-activated protein kinase 10(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to JNK3More data for this Ligand-Target Pair

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Serine/threonine-protein kinase LATS1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LATS1More data for this Ligand-Target Pair

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Serine/threonine-protein kinase LATS2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LATS2More data for this Ligand-Target Pair

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Tyrosine-protein kinase Lck(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LCKMore data for this Ligand-Target Pair

PDB Reactome pathway
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LIM domain kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LIMK1More data for this Ligand-Target Pair

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LIM domain kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LIMK2More data for this Ligand-Target Pair

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Serine/threonine-protein kinase STK11(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LKB1More data for this Ligand-Target Pair

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Leukocyte tyrosine kinase receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LTKMore data for this Ligand-Target Pair

PDB KEGG
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Tyrosine-protein kinase Lyn(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LYNMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to LZKMore data for this Ligand-Target Pair

PDB KEGG
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Mitogen-activated protein kinase kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAP3K1More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 15(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAP3K15More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAP3K2More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAP3K3More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAP4K2More data for this Ligand-Target Pair

MMDB Reactome pathway KEGG
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Mitogen-activated protein kinase kinase kinase kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAP4K3More data for this Ligand-Target Pair

PDB NCI pathway KEGG
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MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAPKAPK2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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MAP kinase-activated protein kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAPKAPK5More data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 12nMAssay Description:Binding affinity to CSF1RMore data for this Ligand-Target Pair

PDB
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Epithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 81nMAssay Description:Binding affinity to DDR1More data for this Ligand-Target Pair

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Discoidin domain-containing receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 690nMAssay Description:Binding affinity to DDR2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Ephrin type-B receptor 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.20E+3nMAssay Description:Binding affinity to EPHB6More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Mitogen-activated protein kinase 15(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 270nMAssay Description:Binding affinity to ERK8More data for this Ligand-Target Pair

KEGG
UniProtKB/SwissProt
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Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding affinity to FLT1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tyrosine-protein kinase FRK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.80E+3nMAssay Description:Binding affinity to FRKMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Homeodomain-interacting protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 320nMAssay Description:Binding affinity to HIPK4More data for this Ligand-Target Pair

KEGG
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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.80nMAssay Description:Binding affinity to KITMore data for this Ligand-Target Pair

PDB Reactome pathway
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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to FLT3More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to cKITMore data for this Ligand-Target Pair

PDB Reactome pathway
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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to PDGFRalphaMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to PDGFRbetaMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to RETMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.60nMAssay Description:Binding affinity to CSF1RMore data for this Ligand-Target Pair

PDB
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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ABL1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tyrosine-protein kinase ABL2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ABL2More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Activin receptor type-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ACVR1More data for this Ligand-Target Pair

PDB KEGG
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Activin receptor type-1B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ACVR1BMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Activin receptor type-2A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ACVR2AMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Activin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ACVR2BMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Serine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ACVRL1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Atypical kinase COQ8A, mitochondrial(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ADCK3More data for this Ligand-Target Pair

PDB KEGG
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Atypical kinase COQ8B, mitochondrial(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ADCK4More data for this Ligand-Target Pair

KEGG
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RAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AKT1More data for this Ligand-Target Pair

PDB Reactome pathway
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RAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AKT2More data for this Ligand-Target Pair

PDB Reactome pathway
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RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AKT3More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AMPK-alpha1More data for this Ligand-Target Pair

PDB Reactome pathway
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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to AMPK-alpha2More data for this Ligand-Target Pair

PDB Reactome pathway
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Ankyrin repeat and protein kinase domain-containing protein 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to ANKK1More data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase MAK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MAKMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase 10(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 9.40E+3nMAssay Description:Binding affinity to LOKMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Mitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.50E+3nMAssay Description:Binding affinity to MAP4K4More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Mitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 440nMAssay Description:Binding affinity to MAP4K5More data for this Ligand-Target Pair

NCI pathway KEGG
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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.60E+3nMAssay Description:Binding affinity to MKNK2More data for this Ligand-Target Pair

PDB MMDB KEGG
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Muscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.00E+3nMAssay Description:Binding affinity to MUSKMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 11nMAssay Description:Binding affinity to PDGFRAMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.70nMAssay Description:Binding affinity to PDGFRBMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 9.90nMAssay Description:Binding affinity to RETMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Mitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 8.50E+3nMAssay Description:Binding affinity to TAK1More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Tyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.20E+3nMAssay Description:Binding affinity to TIE1More data for this Ligand-Target Pair

PDB KEGG
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High affinity nerve growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.30E+3nMAssay Description:Binding affinity to TRKAMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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BDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 620nMAssay Description:Binding affinity to TRKBMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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NT-3 growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 550nMAssay Description:Binding affinity to TRKCMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 87nMAssay Description:Binding affinity to VEGFR2More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Mitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.00E+3nMAssay Description:Binding affinity to YSK4More data for this Ligand-Target Pair

KEGG
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Mitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MLK1More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MLK2More data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MLK3More data for this Ligand-Target Pair

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Serine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MRCKAMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase MRCK beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MRCKBMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MST1More data for this Ligand-Target Pair

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Serine/threonine-protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MST2More data for this Ligand-Target Pair

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Serine/threonine-protein kinase 24(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MST3More data for this Ligand-Target Pair

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Serine/threonine-protein kinase 26(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MST4More data for this Ligand-Target Pair

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Myosin light chain kinase 2, skeletal/cardiac muscle(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MYLK2More data for this Ligand-Target Pair

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Myosin-IIIa(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to MYO3AMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 38(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NDR1More data for this Ligand-Target Pair

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Serine/threonine-protein kinase 38-like(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NDR2More data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NEK1More data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NEK2More data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NEK5More data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase Nek6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NEK6More data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NEK7More data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NEK9More data for this Ligand-Target Pair

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Serine/threonine-protein kinase NIM1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NIM1More data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase NLK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to NLKMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase OSR1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to OSR1More data for this Ligand-Target Pair

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to p38-alphaMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 11(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to p38-betaMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 13(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to p38-deltaMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 12(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to p38-gammaMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PAK1More data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PAK2More data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PAK3More data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding affinity to PAK4More data for this Ligand-Target Pair

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Maternal embryonic leucine zipper kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MELK kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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NUAK family SNF1-like kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ARK5 kinase domainMore data for this Ligand-Target Pair

Reactome pathway KEGG
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Serine/threonine-protein kinase ICK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ICK kinase domainMore data for this Ligand-Target Pair

KEGG
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Microtubule-associated serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAST1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 38-like(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NDR2 kinase domainMore data for this Ligand-Target Pair

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TRAF2 and NCK-interacting protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.80E+3nMAssay Description:Binding constant for TNIK kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 19(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK11 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SIK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 36(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for STK36 kinase domainMore data for this Ligand-Target Pair

NCI pathway KEGG
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Serine/threonine-protein kinase RIO3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RIOK3 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PRP4 homolog(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRP4 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RPS6KA4(Kin.Dom.2-C-terminal) kinase domainMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Cyclin-dependent kinase-like 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDKL2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BRSK2 kinase domainMore data for this Ligand-Target Pair

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Non-receptor tyrosine-protein kinase TNK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TNK1 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Dual specificity protein kinase CLK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CLK3 kinase domainMore data for this Ligand-Target Pair

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Dual specificity protein kinase CLK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CLK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PLK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PLK3 kinase domainMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.10nMAssay Description:Binding constant for FLT3(N841I) kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway
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Cyclin-dependent kinase-like 1 [2-358](Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDKL1 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase 17B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DRAK2 kinase domainMore data for this Ligand-Target Pair

PDB
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Activin receptor type-1B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ACVR1B kinase domainMore data for this Ligand-Target Pair

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ALK tyrosine kinase receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ALK kinase domainMore data for this Ligand-Target Pair

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Bone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BMPR1A kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase B-raf(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BRAF(V600E) kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase CSK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSK kinase domainMore data for this Ligand-Target Pair

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Casein kinase I isoform gamma-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK1G3 kinase domainMore data for this Ligand-Target Pair

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Ephrin type-A receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHA2 kinase domainMore data for this Ligand-Target Pair

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Ephrin type-A receptor 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHA4 kinase domainMore data for this Ligand-Target Pair

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Ephrin type-A receptor 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.70E+3nMAssay Description:Binding constant for EPHA7 kinase domainMore data for this Ligand-Target Pair

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Ephrin type-B receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHB1 kinase domainMore data for this Ligand-Target Pair

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Ephrin type-B receptor 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHB3 kinase domainMore data for this Ligand-Target Pair

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Ephrin type-B receptor 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHB4 kinase domainMore data for this Ligand-Target Pair

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Ephrin type-B receptor 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.20E+3nMAssay Description:Binding constant for EPHB6 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3C2G kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAP4K2 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RSK2(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TGFBR1 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ASK2 kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase LATS1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LATS1 kinase domainMore data for this Ligand-Target Pair

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Dual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DYRK1B kinase domainMore data for this Ligand-Target Pair

PDB
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Mitogen-activated protein kinase kinase kinase 13(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LZK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase DCLK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DCAMKL1 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RPS6KA5(Kin.Dom.2-C-terminal) kinase domainMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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Cyclin-dependent kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK5 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase mTOR(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MTOR kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for JAK2(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CD kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PLK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PLK1 kinase domainMore data for this Ligand-Target Pair

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cAMP-dependent protein kinase catalytic subunit PRKX(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKX kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase OSR1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for OSR1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL1(Q252H)-nonphosphorylated kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ABL2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ABL2 kinase domainMore data for this Ligand-Target Pair

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RAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AKT1 kinase domainMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 10nMAssay Description:Binding constant for CSF1R kinase domainMore data for this Ligand-Target Pair

PDB
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BDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 620nMAssay Description:Binding constant for TRKB kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 16(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PCTK1 kinase domainMore data for this Ligand-Target Pair

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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 11nMAssay Description:Binding constant for PDGFRA kinase domainMore data for this Ligand-Target Pair

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Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PHKG1 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CA(H1047Y) kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CB kinase domainMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AMPK-alpha2 kinase domainMore data for this Ligand-Target Pair

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Protein kinase C delta type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKCD kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase N2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PKN2 kinase domainMore data for this Ligand-Target Pair

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Protein kinase C theta type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKCQ kinase domainMore data for this Ligand-Target Pair

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cGMP-dependent protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKG2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MST2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MST1 kinase domainMore data for this Ligand-Target Pair

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Dual specificity testis-specific protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TESK1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TYRO3 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase VRK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for VRK2 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DLK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 25(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for YSK1 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 440nMAssay Description:Binding constant for MAP4K5 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAP3K2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PLK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PLK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase pim-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIM2 kinase domainMore data for this Ligand-Target Pair

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Citron Rho-interacting kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CIT kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 38(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NDR1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase tousled-like 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TLK1 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 14(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PFTK1 kinase domainMore data for this Ligand-Target Pair

KEGG
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Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIP5K1C kinase domainMore data for this Ligand-Target Pair

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STE20/SPS1-related proline-alanine-rich protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for STK39 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase TBK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TBK1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Sgk3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SGK3 kinase domainMore data for this Ligand-Target Pair

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Inhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for IKK-epsilon kinase domainMore data for this Ligand-Target Pair

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Insulin receptor-related protein(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for INSRR kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PLK4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PLK4 kinase domainMore data for this Ligand-Target Pair

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Death-associated protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DAPK2 kinase domainMore data for this Ligand-Target Pair

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SRSF protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SRPK3 kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase Nek6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK6 kinase domainMore data for this Ligand-Target Pair

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Eukaryotic translation initiation factor 2-alpha kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EIF2AK1 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RSK4(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase LATS2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LATS2 kinase domainMore data for this Ligand-Target Pair

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Hormonally up-regulated neu tumor-associated kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for HUNK kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase ULK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ULK2 kinase domainMore data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for IRAK4 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase TAO2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TAOK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase NLK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NLK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase TAO3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TAOK3 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 26(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MST4 kinase domainMore data for this Ligand-Target Pair

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Myosin-IIIa(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MYO3A kinase domainMore data for this Ligand-Target Pair

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Ephrin type-B receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHB2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase MARK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MARK2 kinase domainMore data for this Ligand-Target Pair

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MAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.60E+3nMAssay Description:Binding constant for MKNK2 kinase domainMore data for this Ligand-Target Pair

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BMP-2-inducible protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BIKE kinase domainMore data for this Ligand-Target Pair

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Transient receptor potential cation channel subfamily M member 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TRPM6 kinase domainMore data for this Ligand-Target Pair

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SNF-related serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SNRK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase RIO2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RIOK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 32B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for YANK2 kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase MARK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MARK1 kinase domainMore data for this Ligand-Target Pair

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Glycogen synthase kinase-3 alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for GSK3A kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PAK6 kinase domainMore data for this Ligand-Target Pair

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Atypical kinase COQ8A, mitochondrial(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ADCK3 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PAK7 kinase domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type 1D(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK1D kinase domainMore data for this Ligand-Target Pair

PDB MMDB KEGG
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Calcium/calmodulin-dependent protein kinase type 1G(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK1G kinase domainMore data for this Ligand-Target Pair

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Ephrin type-A receptor 8(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHA8 kinase domainMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 8nMAssay Description:Binding constant for RET kinase domainMore data for this Ligand-Target Pair

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Receptor-interacting serine/threonine-protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RIPK4 kinase domainMore data for this Ligand-Target Pair

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Dual specificity protein kinase CLK4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CLK4 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase TAO1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TAOK1 kinase domainMore data for this Ligand-Target Pair

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Casein kinase I isoform gamma-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK1G1 kinase domainMore data for this Ligand-Target Pair

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Homeodomain-interacting protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for HIPK2 kinase domainMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FGFR4 kinase domainMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FGFR2 kinase domainMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FGFR1 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIP5K2C kinase domainMore data for this Ligand-Target Pair

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Atypical kinase COQ8B, mitochondrial(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ADCK4 kinase domainMore data for this Ligand-Target Pair

KEGG
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Mitogen-activated protein kinase kinase kinase 19(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.00E+3nMAssay Description:Binding constant for YSK4 kinase domainMore data for this Ligand-Target Pair

KEGG
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Dual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MEK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 33(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for STK33 kinase domainMore data for this Ligand-Target Pair

KEGG
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NUAK family SNF1-like kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SNARK kinase domainMore data for this Ligand-Target Pair

KEGG
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MAP/microtubule affinity-regulating kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MARK4 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase RIO1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RIOK1 kinase domainMore data for this Ligand-Target Pair

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Testis-specific serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TSSK1B kinase domainMore data for this Ligand-Target Pair

KEGG
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Calcium/calmodulin-dependent protein kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMKK1 kinase domainMore data for this Ligand-Target Pair

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MAP kinase-activated protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAPKAPK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK9 kinase domainMore data for this Ligand-Target Pair

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Myosin light chain kinase 2, skeletal/cardiac muscle(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MYLK2 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Mitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MLK1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase DCLK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DCAMKL3 kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase PknB(Mycobacterium tuberculosis)
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PKNB(M.tuberculosis) kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 11B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDC2L1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Srms(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SRMS kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 35(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for STK35 kinase domainMore data for this Ligand-Target Pair

KEGG
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DYRK1A kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK7 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 20(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ZAK kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway KEGG
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Mitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERK2 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 14(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for p38-alpha kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 15(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 270nMAssay Description:Binding constant for ERK8 kinase domainMore data for this Ligand-Target Pair

KEGG
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Casein kinase I isoform delta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK1D kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for JNK2 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 15(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PFTAIRE2 kinase domainMore data for this Ligand-Target Pair

KEGG
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Rhodopsin kinase GRK7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair

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Homeodomain-interacting protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 320nMAssay Description:Binding constant for HIPK4 kinase domainMore data for this Ligand-Target Pair

KEGG
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Dual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MEK5 kinase domainMore data for this Ligand-Target Pair

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Dual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MKK7 kinase domainMore data for this Ligand-Target Pair

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Casein kinase I isoform alpha-like(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK1A1L kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Mitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 8.50E+3nMAssay Description:Binding constant for TAK1 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.50E+3nMAssay Description:Binding constant for MAP4K4 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek11(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK11 kinase domainMore data for this Ligand-Target Pair

KEGG
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Homeodomain-interacting protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for HIPK1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Fyn(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FYN kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase NIM1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NIM1 kinase domainMore data for this Ligand-Target Pair

KEGG
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Focal adhesion kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FAK kinase domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK2G kinase domainMore data for this Ligand-Target Pair

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Protein-tyrosine kinase 2-beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PYK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SIK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 32C(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for YANK3 kinase domainMore data for this Ligand-Target Pair

KEGG
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Ankyrin repeat and protein kinase domain-containing protein 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ANKK1 kinase domainMore data for this Ligand-Target Pair

KEGG
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Ephrin type-A receptor 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EPHA5 kinase domainMore data for this Ligand-Target Pair

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Myosin light chain kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 410nMAssay Description:Binding constant for MLCK kinase domainMore data for this Ligand-Target Pair

KEGG
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Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PKMYT1 kinase domainMore data for this Ligand-Target Pair

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G protein-coupled receptor kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for GRK4 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERK5 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 8(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for JNK1 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 11(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for p38-beta kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 10(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for JNK3 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 13(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for p38-delta kinase domainMore data for this Ligand-Target Pair

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Dual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MEK1 kinase domainMore data for this Ligand-Target Pair

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Dual specificity mitogen-activated protein kinase kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MEK3 kinase domainMore data for this Ligand-Target Pair

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Dual specificity mitogen-activated protein kinase kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MEK6 kinase domainMore data for this Ligand-Target Pair

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Interferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKR kinase domainMore data for this Ligand-Target Pair

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RAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RAF1 kinase domainMore data for this Ligand-Target Pair

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Rhodopsin kinase GRK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for GRK1 kinase domainMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ROS1 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RSK1(Kin.Dom.2-C-terminal) kinase domainMore data for this Ligand-Target Pair

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Dual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MEK4 kinase domainMore data for this Ligand-Target Pair

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SRSF protein kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SRPK1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK4 kinase domainMore data for this Ligand-Target Pair

KEGG
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Cyclin-dependent kinase-like 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDKL5 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase beta-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for S6K1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase SYK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SYK kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Tec(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TEC kinase domainMore data for this Ligand-Target Pair

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TGF-beta receptor type-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TGFBR2 kinase domainMore data for this Ligand-Target Pair

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Dual specificity protein kinase TTK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TTK kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase TXK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TXK kinase domainMore data for this Ligand-Target Pair

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Non-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TYK2(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair

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Wee1-like protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for WEE1 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 5-phosphate 4-kinase type-2 beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIP5K2B kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase ULK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ULK1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 24(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MST3 kinase domainMore data for this Ligand-Target Pair

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Dual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DYRK2 kinase domainMore data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AURKA kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase MRCK alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MRCKA kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAP4K3 kinase domainMore data for this Ligand-Target Pair

PDB NCI pathway KEGG
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Calcium/calmodulin-dependent protein kinase type 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK1 kinase domainMore data for this Ligand-Target Pair

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MAP kinase-activated protein kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAPKAPK5 kinase domainMore data for this Ligand-Target Pair

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Peripheral plasma membrane protein CASK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CASK kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 13(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDC2L5 kinase domainMore data for this Ligand-Target Pair

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Receptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 890nMAssay Description:Binding constant for RIPK1 kinase domainMore data for this Ligand-Target Pair

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Receptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.70E+3nMAssay Description:Binding constant for RIPK2 kinase domainMore data for this Ligand-Target Pair

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Epidermal growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for EGFR(L747-S752del, P753S) kinase domainMore data for this Ligand-Target Pair

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Ephrin type-A receptor 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 6.50E+3nMAssay Description:Binding constant for EPHA3 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Fer(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FER kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Fgr(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FGR kinase domainMore data for this Ligand-Target Pair

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Cyclin-G-associated kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for GAK kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Lck(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.50E+3nMAssay Description:Binding constant for LCK kinase domainMore data for this Ligand-Target Pair

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Protein kinase C epsilon type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKCE kinase domainMore data for this Ligand-Target Pair

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Rho-associated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ROCK1 kinase domainMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SRC kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase receptor Tie-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.20E+3nMAssay Description:Binding constant for TIE1 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Tyrosine-protein kinase Yes(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for YES kinase domainMore data for this Ligand-Target Pair

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RAC-gamma serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AKT3 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ITK kinase domainMore data for this Ligand-Target Pair

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LIM domain kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LIMK2 kinase domainMore data for this Ligand-Target Pair

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Muscle, skeletal receptor tyrosine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.00E+3nMAssay Description:Binding constant for MUSK kinase domainMore data for this Ligand-Target Pair

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Homeodomain-interacting protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for HIPK3 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase D3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKD3 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase MAK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAK kinase domainMore data for this Ligand-Target Pair

KEGG
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Mitogen-activated protein kinase kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAP3K1 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ASK1 kinase domainMore data for this Ligand-Target Pair

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Protein-tyrosine kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BRK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 10(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.10E+3nMAssay Description:Binding constant for LOK kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase MRCK beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MRCKB kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK4CB kinase domainMore data for this Ligand-Target Pair

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cAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PKAC-alpha kinase domainMore data for this Ligand-Target Pair

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cAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PKAC-beta kinase domainMore data for this Ligand-Target Pair

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Protein kinase C iota type(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKCI kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase D1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PRKD1 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERK1 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERK4 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 6(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERK3 kinase domainMore data for this Ligand-Target Pair

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Fibroblast growth factor receptor 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FGFR3 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for JAK3(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 5nMAssay Description:Binding constant for KIT(V559D) kinase domainMore data for this Ligand-Target Pair

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Hepatocyte growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MET(M1250T) kinase domainMore data for this Ligand-Target Pair

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Phosphorylase b kinase gamma catalytic chain, liver/testis isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PHKG2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase STK11(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LKB1 kinase domainMore data for this Ligand-Target Pair

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Angiopoietin-1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair

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Insulin-like growth factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for IGF1R kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 15(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAP3K15 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase pim-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIM3 kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase Chk2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CHEK2 kinase domainMore data for this Ligand-Target Pair

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Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERBB2 kinase domainMore data for this Ligand-Target Pair

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Ribosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RSK3(Kin.Dom.1-N-terminal) kinase domainMore data for this Ligand-Target Pair

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Activated CDC42 kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TNK2 kinase domainMore data for this Ligand-Target Pair

PDB MMDB KEGG
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High affinity nerve growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.30E+3nMAssay Description:Binding constant for TRKA kinase domainMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway
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Myosin light chain kinase family member 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MYLK4 kinase domainMore data for this Ligand-Target Pair

PDB MMDB KEGG
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Serine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PAK4 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SBK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SBK1 kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase DCLK2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DCAMKL2 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Receptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERBB4 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for HPK1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase ULK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ULK3 kinase domainMore data for this Ligand-Target Pair

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Activin receptor type-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ACVR1 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Activin receptor type-2B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ACVR2B kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase 32A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for YANK1 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Cyclin-dependent kinase-like 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDKL3 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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MAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MKNK1 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIP5K1A kinase domainMore data for this Ligand-Target Pair

NCI pathway Reactome pathway KEGG
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Bone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BMPR1B kinase domainMore data for this Ligand-Target Pair

PDB
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Bone morphogenetic protein receptor type-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BMPR2 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Cyclin-dependent kinase 8(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK8 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 9(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK9 kinase domainMore data for this Ligand-Target Pair

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Casein kinase I isoform gamma-2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK1G2 kinase domainMore data for this Ligand-Target Pair

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Death-associated protein kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for DAPK3 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase/endoribonuclease IRE1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERN1 kinase domainMore data for this Ligand-Target Pair

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Inhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for IKK-beta kinase domainMore data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for IRAK1 kinase domainMore data for this Ligand-Target Pair

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Activin receptor type-2A(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ACVR2A kinase domainMore data for this Ligand-Target Pair

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RAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AKT2 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AXL kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Blk(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BLK kinase domainMore data for this Ligand-Target Pair

Reactome pathway KEGG
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Cytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BMX kinase domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK4 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 2(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK2 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 7(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK7 kinase domainMore data for this Ligand-Target Pair

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Casein kinase I isoform alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK1A1 kinase domainMore data for this Ligand-Target Pair

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Casein kinase I isoform epsilon(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK1E kinase domainMore data for this Ligand-Target Pair

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Casein kinase II subunit alpha(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK2A1 kinase domainMore data for this Ligand-Target Pair

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Casein kinase II subunit alpha'(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CSNK2A2 kinase domainMore data for this Ligand-Target Pair

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Epithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 81nMAssay Description:Binding constant for DDR1 kinase domainMore data for this Ligand-Target Pair

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Receptor tyrosine-protein kinase erbB-3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ERBB3 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Fes/Fps(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for FES kinase domainMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding constant for FLT1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase FRK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.80E+3nMAssay Description:Binding constant for FRK kinase domainMore data for this Ligand-Target Pair

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Glycogen synthase kinase-3 beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for GSK3B kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase HCK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for HCK kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for JAK1(JH1domain-catalytic) kinase domainMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 87nMAssay Description:Binding constant for VEGFR2 kinase domainMore data for this Ligand-Target Pair

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LIM domain kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LIMK1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Lyn(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 5.70E+3nMAssay Description:Binding constant for LYN kinase domainMore data for this Ligand-Target Pair

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Megakaryocyte-associated tyrosine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CTK kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MAP3K3 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MLK3 kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase kinase kinase 10(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MLK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK3 kinase domainMore data for this Ligand-Target Pair

KEGG
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Serine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PAK1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PAK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase PAK 3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PAK3 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 18 [3-474](Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PCTK3 kinase domainMore data for this Ligand-Target Pair

KEGG
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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.70nMAssay Description:Binding constant for PDGFRB kinase domainMore data for this Ligand-Target Pair

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3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PDPK1 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3C2B kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase pim-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIM1 kinase domainMore data for this Ligand-Target Pair

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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PIK3CG kinase domainMore data for this Ligand-Target Pair

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Leucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LRRK2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase Nek5(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for NEK5 kinase domainMore data for this Ligand-Target Pair

KEGG
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Leukocyte tyrosine kinase receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for LTK kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Tyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ZAP70 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase N1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PKN1 kinase domainMore data for this Ligand-Target Pair

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Wee1-like protein kinase 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for WEE2 kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Uncharacterized serine/threonine-protein kinase SBK3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for SgK110 kinase domainMore data for this Ligand-Target Pair

KEGG
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Calcium-dependent protein kinase 1(Plasmodium Falciparum)
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PFCDPK1(P.falciparum) kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 2 homolog(Plasmodium falciparum (isolate 3D7))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PFPK5(P.falciparum) kinase domainMore data for this Ligand-Target Pair

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Dual serine/threonine and tyrosine protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for RIPK5 kinase domainMore data for this Ligand-Target Pair

KEGG
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STE20-like serine/threonine-protein kinase(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.60E+3nMAssay Description:Binding constant for SLK kinase domainMore data for this Ligand-Target Pair

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Dual specificity protein kinase CLK1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CLK1 kinase domainMore data for this Ligand-Target Pair

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NT-3 growth factor receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 550nMAssay Description:Binding constant for TRKC kinase domainMore data for this Ligand-Target Pair

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Mitogen-activated protein kinase 12(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for p38-gamma kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase Mer(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for MERTK kinase domainMore data for this Ligand-Target Pair

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Aurora kinase C(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AURKC kinase domainMore data for this Ligand-Target Pair

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Calcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CAMK2D kinase domainMore data for this Ligand-Target Pair

PDB
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Serine/threonine-protein kinase tousled-like 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for TLK2 kinase domainMore data for this Ligand-Target Pair

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5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for AMPK-alpha1 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase SIK3 [59-1321](Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for QSK kinase domainMore data for this Ligand-Target Pair

PDB KEGG
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Serine/threonine-protein kinase 16(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for STK16 kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 17(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for PCTK2 kinase domainMore data for this Ligand-Target Pair

KEGG
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Discoidin domain-containing receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.10E+3nMAssay Description:Binding constant for DDR2 kinase domainMore data for this Ligand-Target Pair

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Serine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for ACVRL1 kinase domainMore data for this Ligand-Target Pair

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Tyrosine-protein kinase BTK(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for BTK kinase domainMore data for this Ligand-Target Pair

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Cyclin-dependent kinase 4(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >1.00E+4nMAssay Description:Binding constant for CDK4-cyclinD1 kinase domainMore data for this Ligand-Target Pair

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Epithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 81nMAssay Description:Binding affinity to DDR1 (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 3(Homo sapiens (Human))
Korea University

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding affinity to FLT4 (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 11nMAssay Description:Binding affinity to PDGFRalpha (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.70nMAssay Description:Binding affinity to PDGFRbeta (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.80nMAssay Description:Binding affinity to KIT (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 12nMAssay Description:Binding affinity to CSF1R (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

PDB
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Discoidin domain-containing receptor 2(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 690nMAssay Description:Binding affinity to DDR2 (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 9.90nMAssay Description:Binding affinity to RET (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Vascular endothelial growth factor receptor 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 41nMAssay Description:Binding affinity to FLT1 (unknown origin) by KinomeSCan assayMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 8.80nMAssay Description:Binding affinity to human FLT3 ITD mutant expressed in baculovirus expression systemMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.30nMAssay Description:Binding affinity to non-auto-inhibited form of wild type human N-terminal GST-tagged FLT3 expressed in baculovirus expressionMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.70nMAssay Description:Binding affinity to human FLT3 D835H mutant expressed in baculovirus expression systemMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 8.80nMAssay Description:Binding affinity to FLT3 ITD mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.70nMAssay Description:Binding affinity to FLT3 D835H mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.10nMAssay Description:Binding affinity to FLT3 D835Y mutant (unknown origin)More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.30nMAssay Description:Binding affinity to wild type FLT3 (unknown origin)More data for this Ligand-Target Pair

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Macrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 15nMAssay Description:Binding affinity to recombinant human CSF1R (564 to 939 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.30nMAssay Description:Binding affinity to recombinant human FLT3 (592 to 969 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.60nMAssay Description:Binding affinity to recombinant human FLT3 ITD mutant expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 420nMAssay Description:Binding affinity to recombinant human FLT3 ITD/D835V double mutant expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 55nMAssay Description:Binding affinity to recombinant human FLT3 ITD/F691L double mutant expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Mast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.60nMAssay Description:Binding affinity to recombinant human KIT (571 to 972 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Platelet-derived growth factor receptor alpha(Homo sapiens (Human))
Palack£

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.60nMAssay Description:Binding affinity to recombinant human PDGFRA (575 to 1002 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Platelet-derived growth factor receptor beta(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4nMAssay Description:Binding affinity to recombinant human PDGFRB (582 to 1009 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Proto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 3.80nMAssay Description:Binding affinity to recombinant human RET (713 to 1014 residues) expressed in bacterial expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 340nMAssay Description:Binding affinity to human partial length FLT3 ITD/F691L double mutant expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.40nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3 [D835H](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 2.10nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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3D Structure (crystal)

Receptor-type tyrosine-protein kinase FLT3 [D835V](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 4.20nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3 [D835Y](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7.60nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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3D Structure (crystal)

Dimer of Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 7nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 480nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 160nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 0.570nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3 [N841I](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 1.5nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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3D Structure (crystal)

Receptor-type tyrosine-protein kinase FLT3 [R834Q](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 12nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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3D Structure (crystal)

Receptor-type tyrosine-protein kinase FLT3 [564-710,762-958](Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 580nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >3.00E+4nMAssay Description:Table 7 For most assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phas...More data for this Ligand-Target Pair

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Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Children'S Hospital Medical Center

US Patent

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: >3.00E+4nMAssay Description:Table 8-10: Compounds were tested in 10-dose IC50 mode with 3-fold serial dilution starting at 10 uM, and are relative to DMSO, the negative control....More data for this Ligand-Target Pair

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Receptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ambit Biosciences

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

Kd: 890nMAssay Description:Binding affinity to RIPK1 (unknown origin)More data for this Ligand-Target Pair

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Displayed 1 to 50 (of 940 total ) | Next | Last >>

Filter my 940 hits

Targets 392▿
- Receptor-type tyrosine-protein kinase FLT3 75
- Tyrosine-protein kinase ABL1 16
- Mast/stem cell growth factor receptor Kit 13
- Epidermal growth factor receptor 13
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 11
- Proto-oncogene tyrosine-protein kinase receptor Ret 11
- Platelet-derived growth factor receptor beta 8
- Platelet-derived growth factor receptor alpha 8
- Macrophage colony-stimulating factor 1 receptor 6
- Vascular endothelial growth factor receptor 2 6
- Interleukin-1 receptor-associated kinase 1 5
- Aurora kinase A 5
- Vascular endothelial growth factor receptor 3 5
- Vascular endothelial growth factor receptor 1 5
- Interleukin-1 receptor-associated kinase 4 4
- Tyrosine-protein kinase Lck 4
- Ephrin type-A receptor 6 4
- Tyrosine-protein kinase JAK1 4
- Ribosomal protein S6 kinase alpha-6 4
- Tyrosine-protein kinase Blk 4
- Ribosomal protein S6 kinase alpha-4 4
- Ribosomal protein S6 kinase alpha-5 4
- Ribosomal protein S6 kinase alpha-2 4
- Ribosomal protein S6 kinase alpha-1 4
- SRSF protein kinase 1 4
- Hepatocyte growth factor receptor 4
- Epithelial discoidin domain-containing receptor 1 4
- Non-receptor tyrosine-protein kinase TYK2 4
- Mitogen-activated protein kinase 14 4
- Cyclin-dependent kinase 2 3
- Discoidin domain-containing receptor 2 3
- Dimer of Receptor-type tyrosine-protein kinase FLT3 3
- Cyclin-H/Cyclin-dependent kinase 7 3
- Myosin light chain kinase, smooth muscle 3
- Serine/threonine-protein kinase B-raf 3
- Receptor-interacting serine/threonine-protein kinase 1 3
- Serine/threonine-protein kinase TAO1 3
- Calcium/calmodulin-dependent protein kinase type II subunit gamma 3
- Receptor-type tyrosine-protein kinase FLT3 [D835Y] 3
- Fibroblast growth factor receptor 3 3
- Tyrosine-protein kinase Tec 2
- BMP-2-inducible protein kinase 2
- Rhodopsin kinase GRK1 2
- Cyclin-dependent kinase 11B 2
- Cyclin-dependent kinase 11A 2
- Uncharacterized serine/threonine-protein kinase SBK3 2
- LIM domain kinase 1 2
- LIM domain kinase 2 2
- ALK tyrosine kinase receptor 2
- NUAK family SNF1-like kinase 2 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 2
- Glycogen synthase kinase-3 beta 2
- Calcium/calmodulin-dependent protein kinase type 1 2
- NUAK family SNF1-like kinase 1 2
- Calcium/calmodulin-dependent protein kinase type II subunit beta 2
- AP2-associated protein kinase 1 2
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2
- Serine/threonine-protein kinase PAK 1 2
- Protein kinase C theta type 2
- Serine/threonine-protein kinase PAK 2 2
- Serine/threonine-protein kinase PAK 3 2
- Dual specificity mitogen-activated protein kinase kinase 2 2
- Serine/threonine-protein kinase PAK 4 2
- Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 2
- Serine/threonine-protein kinase tousled-like 2 2
- Dual specificity mitogen-activated protein kinase kinase 3 2
- Serine/threonine-protein kinase PAK 5 2
- Serine/threonine-protein kinase PAK 6 2
- Serine/threonine-protein kinase tousled-like 1 2
- Tyrosine-protein kinase JAK3 2
- Tyrosine-protein kinase JAK2 2
- Dual specificity mitogen-activated protein kinase kinase 1 2
- Dual specificity mitogen-activated protein kinase kinase 6 2
- Dual specificity mitogen-activated protein kinase kinase 4 2
- Leucine-rich repeat serine/threonine-protein kinase 2 2
- Tyrosine-protein kinase ZAP-70 2
- Casein kinase I isoform gamma-3 2
- Casein kinase I isoform gamma-2 2
- Casein kinase I isoform epsilon 2
- Casein kinase I isoform gamma-1 2
- Ephrin type-A receptor 1 2
- Ephrin type-A receptor 3 2
- Ephrin type-A receptor 2 2
- Ephrin type-A receptor 5 2
- Tyrosine-protein kinase BTK 2
- Ephrin type-A receptor 4 2
- Tyrosine-protein kinase receptor UFO 2
- Insulin-like growth factor 1 receptor 2
- Activin receptor type-1 2
- Myosin light chain kinase 2, skeletal/cardiac muscle 2
- Tyrosine-protein kinase Srms 2
- Wee1-like protein kinase 2
- Serine/threonine-protein kinase MAK 2
- Serine/threonine-protein kinase/endoribonuclease IRE1 2
- Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma 2
- Ankyrin repeat and protein kinase domain-containing protein 1 2
- Tyrosine-protein kinase Lyn 2
- Focal adhesion kinase 1 2
- Tyrosine-protein kinase TXK 2
- Rhodopsin kinase GRK7 2
- Ephrin type-A receptor 8 2
- Phosphatidylinositol 4-kinase beta 2
- Death-associated protein kinase 2 2
- Death-associated protein kinase 1 2
- Serine/threonine-protein kinase D2 2
- Serine/threonine-protein kinase D3 2
- TGF-beta receptor type-2 2
- Serine/threonine-protein kinase D1 2
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B 2
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2
- Death-associated protein kinase 3 2
- Cyclin-dependent kinase 9 2
- Cyclin-dependent kinase 8 2
- Serine/threonine-protein kinase pim-3 2
- Cyclin-dependent kinase 7 2
- Serine/threonine-protein kinase pim-1 2
- Cyclin-dependent kinase 5 2
- Serine/threonine-protein kinase pim-2 2
- Serine/threonine-protein kinase 38 2
- Cyclin-dependent kinase 4 2
- Serine/threonine-protein kinase 35 2
- Cyclin-dependent kinase 3 2
- Serine/threonine-protein kinase 36 2
- Testis-specific serine/threonine-protein kinase 1 2
- Cyclin-dependent kinase 16 2
- Protein kinase C epsilon type 2
- Cyclin-dependent kinase 17 2
- Bone morphogenetic protein receptor type-2 2
- Cyclin-dependent kinase 19 2
- Protein-tyrosine kinase 6 2
- Casein kinase II subunit alpha 2
- Cyclin-dependent kinase 14 2
- Cyclin-dependent kinase 15 2
- Leukocyte tyrosine kinase receptor 2
- Cytoplasmic tyrosine-protein kinase BMX 2
- Tyrosine-protein kinase ABL2 2
- Atypical kinase COQ8B, mitochondrial 2
- Microtubule-associated serine/threonine-protein kinase 1 2
- Calcium/calmodulin-dependent protein kinase type II subunit alpha 2
- cGMP-dependent protein kinase 2 2
- Rho-associated protein kinase 2 2
- cGMP-dependent protein kinase 1 2
- Rho-associated protein kinase 1 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2
- Serine/threonine-protein kinase ULK1 2
- Serine/threonine-protein kinase SIK2 2
- Tyrosine-protein kinase Fes/Fps 2
- Serine/threonine-protein kinase SIK1 2
- Serine/threonine-protein kinase ULK2 2
- Serine/threonine-protein kinase ULK3 2
- 3-phosphoinositide-dependent protein kinase 1 2
- Mitogen-activated protein kinase 1 2
- Serine/threonine-protein kinase 3 2
- Mitogen-activated protein kinase 3 2
- Mitogen-activated protein kinase 4 2
- Serine/threonine-protein kinase 4 2
- SRSF protein kinase 3 2
- Mitogen-activated protein kinase 9 2
- SRSF protein kinase 2 2
- Mitogen-activated protein kinase 6 2
- Mitogen-activated protein kinase 7 2
- Mitogen-activated protein kinase 8 2
- Calcium/calmodulin-dependent protein kinase type IV 2
- Tyrosine-protein kinase SYK 2
- Serine/threonine-protein kinase TBK1 2
- Serine/threonine-protein kinase RIO1 2
- Serine/threonine-protein kinase LATS1 2
- Serine/threonine-protein kinase RIO3 2
- Serine/threonine-protein kinase 32B 2
- Serine/threonine-protein kinase RIO2 2
- Serine/threonine-protein kinase 32C 2
- Insulin receptor 2
- Tyrosine-protein kinase HCK 2
- Serine/threonine-protein kinase PLK1 2
- Serine/threonine-protein kinase PLK2 2
- Insulin receptor-related protein 2
- Inhibitor of nuclear factor kappa-B kinase subunit beta 2
- Serine/threonine-protein kinase PLK3 2
- Serine/threonine-protein kinase NIM1 2
- Serine/threonine-protein kinase PLK4 2
- Tyrosine-protein kinase receptor TYRO3 2
- Wee1-like protein kinase 2 2
- Serine/threonine-protein kinase BRSK1 2
- Serine/threonine-protein kinase LATS2 2
- Citron Rho-interacting kinase 2
- Serine/threonine-protein kinase BRSK2 2
- Serine/threonine-protein kinase Chk2 2
- Serine/threonine-protein kinase Chk1 2
- cAMP-dependent protein kinase catalytic subunit PRKX 2
- Tyrosine-protein kinase Yes 2
- Serine/threonine-protein kinase MRCK beta 2
- Serine/threonine-protein kinase MRCK gamma 2
- Casein kinase II subunit alpha' 2
- Dual specificity tyrosine-phosphorylation-regulated kinase 2 2
- Serine/threonine-protein kinase STK11 2
- Cyclin-G-associated kinase 2
- Receptor tyrosine-protein kinase erbB-4 2
- Tyrosine-protein kinase FRK 2
- Receptor tyrosine-protein kinase erbB-2 2
- Receptor tyrosine-protein kinase erbB-3 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 2
- Serine/threonine-protein kinase Nek9 2
- Serine/threonine-protein kinase Nek7 2
- Glycogen synthase kinase-3 alpha 2
- Serine/threonine-protein kinase Nek6 2
- Serine/threonine-protein kinase Nek5 2
- Serine/threonine-protein kinase Nek2 2
- Serine/threonine-protein kinase Nek1 2
- Serine/threonine-protein kinase receptor R3 2
- Macrophage-stimulating protein receptor 2
- Cyclin-dependent kinase-like 3 2
- Cyclin-dependent kinase-like 2 2
- Serine/threonine-protein kinase SIK3 [59-1321] 2
- MAP/microtubule affinity-regulating kinase 3 2
- Homeodomain-interacting protein kinase 4 2
- Homeodomain-interacting protein kinase 3 2
- MAP kinase-interacting serine/threonine-protein kinase 2 2
- MAP kinase-interacting serine/threonine-protein kinase 1 2
- Cyclin-dependent kinase-like 5 2
- Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 2
- MAP/microtubule affinity-regulating kinase 4 2
- Serine/threonine-protein kinase 10 2
- Serine/threonine-protein kinase 38-like 2
- Dual specificity protein kinase TTK 2
- Myosin-IIIb 2
- Myosin-IIIa 2
- Tyrosine-protein kinase ITK/TSK 2
- Myotonin-protein kinase 2
- Protein kinase C eta type 2
- Bone morphogenetic protein receptor type-1B 2
- Bone morphogenetic protein receptor type-1A 2
- Receptor-interacting serine/threonine-protein kinase 2 2
- Serine/threonine-protein kinase 16 2
- Non-receptor tyrosine-protein kinase TNK1 2
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 2
- Serine/threonine-protein kinase NLK 2
- Homeodomain-interacting protein kinase 2 2
- Homeodomain-interacting protein kinase 1 2
- Receptor-interacting serine/threonine-protein kinase 4 2
- Ribosomal protein S6 kinase beta-1 2
- Serine/threonine-protein kinase OSR1 2
- Casein kinase I isoform delta 2
- Cyclin-dependent kinase 18 [3-474] 2
- RAF proto-oncogene serine/threonine-protein kinase 2
- Serine/threonine-protein kinase 26 2
- Serine/threonine-protein kinase 24 2
- Dual specificity testis-specific protein kinase 1 2
- Serine/threonine-protein kinase 25 2
- Ephrin type-B receptor 3 2
- Serine/threonine-protein kinase 33 2
- Ephrin type-B receptor 4 2
- Ephrin type-B receptor 1 2
- Ephrin type-B receptor 2 2
- Ephrin type-B receptor 6 2
- MAP kinase-activated protein kinase 2 2
- MAP kinase-activated protein kinase 5 2
- STE20/SPS1-related proline-alanine-rich protein kinase 2
- Muscle, skeletal receptor tyrosine-protein kinase 2
- Tyrosine-protein kinase Fer 2
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 2
- Tyrosine-protein kinase receptor Tie-1 2
- Calcium/calmodulin-dependent protein kinase type II subunit delta 2
- Proto-oncogene tyrosine-protein kinase ROS 2
- Calcium/calmodulin-dependent protein kinase kinase 1 2
- Serine/threonine-protein kinase DCLK1 2
- Serine/threonine-protein kinase TAO3 2
- Calcium/calmodulin-dependent protein kinase kinase 2 2
- Serine/threonine-protein kinase DCLK2 2
- Serine/threonine-protein kinase DCLK3 2
- Angiopoietin-1 receptor 2
- Serine/threonine-protein kinase TNNI3K 2
- Interferon-induced, double-stranded RNA-activated protein kinase 2
- Mitogen-activated protein kinase kinase kinase kinase 2 2
- Mitogen-activated protein kinase kinase kinase kinase 3 2
- Mitogen-activated protein kinase kinase kinase kinase 1 2
- Serine/threonine-protein kinase MRCK alpha 2
- Mitogen-activated protein kinase kinase kinase kinase 4 2
- Mitogen-activated protein kinase kinase kinase kinase 5 2
- Mitogen-activated protein kinase 15 2
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 2
- Activin receptor type-1B 2
- Myosin light chain kinase family member 4 2
- Mitogen-activated protein kinase kinase kinase 9 2
- RAC-gamma serine/threonine-protein kinase 2
- Mitogen-activated protein kinase kinase kinase 6 2
- Mitogen-activated protein kinase kinase kinase 5 2
- Interleukin-1 receptor-associated kinase 3 2
- Mitogen-activated protein kinase kinase kinase 7 2
- Mitogen-activated protein kinase kinase kinase 2 2
- Mitogen-activated protein kinase kinase kinase 1 2
- Mitogen-activated protein kinase kinase kinase 4 2
- Mitogen-activated protein kinase kinase kinase 3 2
- Serine/threonine-protein kinase ICK 2
- RAC-alpha serine/threonine-protein kinase 2
- Megakaryocyte-associated tyrosine-protein kinase 2
- Proto-oncogene tyrosine-protein kinase Src 2
- Activin receptor type-2B 2
- Activin receptor type-2A 2
- BDNF/NT-3 growth factors receptor 2
- Serine/threonine-protein kinase 17A 2
- Serine/threonine-protein kinase 17B 2
- Mitogen-activated protein kinase kinase kinase 19 2
- Dual specificity protein kinase CLK1 2
- Mitogen-activated protein kinase kinase kinase 15 2
- Protein kinase C delta type 2
- NT-3 growth factor receptor 2
- Dual specificity protein kinase CLK4 2
- G protein-coupled receptor kinase 4 2
- Dual specificity protein kinase CLK3 2
- Dual specificity protein kinase CLK2 2
- Protein-tyrosine kinase 2-beta 2
- High affinity nerve growth factor receptor 2
- Tyrosine-protein kinase Mer 2
- Serine/threonine-protein kinase N2 2
- cAMP-dependent protein kinase catalytic subunit beta 2
- Serine/threonine-protein kinase N1 2
- Ribosomal protein S6 kinase alpha-3 2
- Calcium/calmodulin-dependent protein kinase type 1D 2
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 2
- STE20-like serine/threonine-protein kinase 2
- Hormonally up-regulated neu tumor-associated kinase 2
- Fibroblast growth factor receptor 4 2
- Tyrosine-protein kinase Fgr 2
- Aurora kinase B 2
- Mitogen-activated protein kinase kinase kinase 20 2
- Fibroblast growth factor receptor 1 2
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 2
- Fibroblast growth factor receptor 2 2
- Atypical kinase COQ8A, mitochondrial 2
- Aurora kinase C 2
- Mitogen-activated protein kinase 13 2
- Mitogen-activated protein kinase 12 2
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 2
- Mitogen-activated protein kinase 11 2
- Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 2
- RAC-beta serine/threonine-protein kinase 2
- Mitogen-activated protein kinase 10 2
- Casein kinase I isoform alpha 2
- Misshapen-like kinase 1 2
- Tyrosine-protein kinase Fyn 2
- Tyrosine-protein kinase CSK 2
- Maternal embryonic leucine zipper kinase 2
- Serine/threonine-protein kinase MARK1 2
- Serine/threonine-protein kinase MARK2 2
- TRAF2 and NCK-interacting protein kinase 2
- Mitogen-activated protein kinase kinase kinase 13 2
- Mitogen-activated protein kinase kinase kinase 10 2
- Mitogen-activated protein kinase kinase kinase 11 2
- Calcium-dependent protein kinase 1 1
- Serine/threonine-protein kinase Nek11 1
- Cyclin-A1/Cyclin-dependent kinase 2 1
- Peripheral plasma membrane protein CASK 1
- Serine/threonine-protein kinase mTOR 1
- Eukaryotic translation initiation factor 2-alpha kinase 1 1
- Dual serine/threonine and tyrosine protein kinase 1
- Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 1
- Poly [ADP-ribose] polymerase tankyrase-2 1
- Serine/threonine-protein kinase PknB 1
- Receptor-type tyrosine-protein kinase FLT3 [D835H] 1
- SNF-related serine/threonine-protein kinase 1
- Serine/threonine-protein kinase PRP4 homolog 1
- Serine/threonine-protein kinase TAO2 1
- Cyclin-dependent kinase-like 1 [2-358] 1
- Cyclin-dependent kinase 2 homolog 1
- Casein kinase I isoform alpha-like 1
- Calcium/calmodulin-dependent protein kinase type 1G 1
- Serine/threonine-protein kinase 32A 1
- Cyclin-dependent kinase 13 1
- Protein kinase C iota type 1
- Transient receptor potential cation channel subfamily M member 6 1
- Serine/threonine-protein kinase Nek4 1
- U4/U6 small nuclear ribonucleoprotein Prp4 1
- Serine/threonine-protein kinase Nek3 1
- Serine/threonine-protein kinase VRK2 1
- cAMP-dependent protein kinase catalytic subunit alpha 1
- Protein kinase C alpha type 1
- eIF-2-alpha kinase GCN2 1
- Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 1
- Receptor-type tyrosine-protein kinase FLT3 [N841I] 1
- Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L] 1
- Serine/threonine-protein kinase SBK1 1
- Receptor-type tyrosine-protein kinase FLT3 [564-710,762-958] 1
- Protein delta homolog 1 1
- Activated CDC42 kinase 1 1
- Dual specificity mitogen-activated protein kinase kinase 7 1
- Dual specificity mitogen-activated protein kinase kinase 5 1
- Mitogen-activated protein kinase kinase kinase 12 1
- Receptor-type tyrosine-protein kinase FLT3 [D835V] 1
- Receptor-type tyrosine-protein kinase FLT3 [R834Q] 1
- Serine/threonine-protein kinase Sgk3 1
- Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V] 1
- Myosin light chain kinase 3 1
- ...
Publications 35▿
- Nat Biotechnol 29: 1046-51 (2011) 442
- Blood 114: 2984-92 (2009) 361
- US Patent US11542261 (2023) 36
- J Med Chem 60: 8407-8424 (2017) 10
- ACS Med Chem Lett 11: 1567-1572 (2020) 10
- J Med Chem 52: 7808-16 (2009) 10
- J Med Chem 53: 6779-810 (2010) 6
- Eur J Med Chem 184: (2019) 5
- J Med Chem 59: 6187-200 (2016) 5
- Bioorg Med Chem Lett 22: 4654-9 (2012) 4
- Bioorg Med Chem Lett 30: (2020) 3
- Eur J Med Chem 100: 151-61 (2015) 3
- Bioorg Med Chem 48: (2021) 3
- J Med Chem 61: 3855-3869 (2018) 3
- J Med Chem 62: 2428-2446 (2019) 3
- J Med Chem 62: 9141-9160 (2019) 3
- Eur J Med Chem 193: (2020) 3
- Bioorg Med Chem Lett 60: (2022) 3
- Bioorg Med Chem 56: (2022) 2
- Eur J Med Chem 235: (2022) 2
- ACS Med Chem Lett 7: 476-81 (2016) 2
- Bioorg Med Chem 21: 2856-67 (2013) 2
- J Med Chem 64: 10981-10996 (2021) 2
- Eur J Med Chem 85: 399-407 (2014) 2
- US Patent US9216997 (2015) 1
- J Med Chem 65: 14971-14999 (2022) 1
- J Med Chem 62: 4158-4173 (2019) 1
- Bioorg Med Chem Lett 30: (2020) 1
- Bioorg Med Chem Lett 27: 496-500 (2017) 1
- Eur J Med Chem 94: 123-31 (2015) 1
- Eur J Med Chem 195: (2020) 1
- Eur J Med Chem 120: 74-85 (2016) 1
- Eur J Med Chem 182: (2019) 1
- US Patent US10266535 (2019) 1
- Bioorg Med Chem Lett 24: 2655-60 (2014) 1
Institutions 26▿
- Ambit Biosciences 813
- Children'S Hospital Medical Center 36
- Chinese Academy of Sciences 10
- Jinan University 10
- National Health Research Institutes 9
- Palack£ 7
- Aristotle University Of Thessaloniki 6
- East China University Of Science & Technology 5
- Vichem Chemie Research 5
- Yonsei University 5
- Korea University 3
- Technische Universit£T Darmstadt 3
- University Of Regensburg 3
- Chinese Academy Of Sciences 3
- Sichuan University 3
- Ain Shams University 2
- University Of Palermo 2
- Purdue University 2
- Harvard Medical School 2
- West China Hospital 1
- TBA 1
- The University Of Arizona 1
- Gwangju Institute Of Science And Technology 1
- Hefei Institutes of Physical Science, Chinese Academy of Sciences 1
- Shanghai De Novo Pharmatech 1
- Jiangnan University 1
Affinity: 0.0020 to 3.0E+4 nM▿
- IC50 83
- Kd 857
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1