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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Proton-coupled amino acid transporter 1
(Homo sapiens (Human))
Martin-Luther-University Halle-Wittenberg
Curated by
ChEMBL
Ligand
BDBM50219348
((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
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Affinity Data
Ki: 1.00E+8nM
Assay Description:
Inhibition of human PAT1-mediated L-[3H]proline uptake in human Caco2 cells after 10 mins by liquid scintillation counting
Checked by Author
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Target Info
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Target
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by
ChEMBL
Ligand
BDBM50219348
((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of TNAP by analogous luminescence assay
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
Phospholipase A-2-activating protein
(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by
ChEMBL
Ligand
BDBM50219348
((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of PLAP by analogous luminescence assay
More data for this Ligand-Target Pair
Target Info
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MMDB
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antibodypedia
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Target
Intestinal-type alkaline phosphatase
(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by
ChEMBL
Ligand
BDBM50219348
((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of IAP by analogous luminescence assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
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ChEBI
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Target
Large neutral amino acids transporter small subunit 1
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50219348
((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
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Affinity Data
IC50: 8.50E+4nM
Assay Description:
Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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ChEBI
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KEGG
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Article
PubMed
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Target
Large neutral amino acids transporter small subunit 1
(Homo sapiens (Human))
University Of California
Curated by
ChEMBL
Ligand
BDBM50219348
((2S)-2-amino-4-methylpentanoic acid | (S)-(+)-leuc...)
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Affinity Data
IC50: 8.70E+4nM
Assay Description:
Inhibition of human LAT1 expressed in HEK293-T-Rex cells assessed as inhibition of [3H]-gabapentin uptake by scintillation counting cis-inhibition as...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
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PC sid
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In Depth
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Article
PubMed
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