Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 20 hits in this display   

TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  4nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  4nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194225(US9200006, 3)
Affinity DataKi:  4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi: <50nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194225(US9200006, 3)
Affinity DataKi: <50nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin K(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi: <50nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  750nMAssay Description:The enzyme is commercially available human cathepsin L. The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assay buffer is 100 mM sodium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  750nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194225(US9200006, 3)
Affinity DataKi:  751nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194225(US9200006, 3)
Affinity DataKi:  1.40E+3nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  1.40E+3nMAssay Description:The enzyme is commercially available human cathepsin L. The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assay buffer is 100 mM sodium...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  1.40E+3nMAssay Description:The enzyme is commercially available human cathepsin L (for example Calbiochem). The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProcathepsin L(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  1.40E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194225(US9200006, 3)
Affinity DataKi: >1.00E+4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi: >1.00E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  2.05E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  2.20E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM194225(US9200006, 3)
Affinity DataKi:  2.20E+4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Medivir

US Patent
LigandPNGBDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Affinity DataKi:  2.20E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
In DepthDetails US Patent