Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 20 hits in this display
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: <50nMAssay Description:The recombinant cathepsin K can be expressed in a variety of commercially available expression systems including E coli, Pichia and Baculovirus syste...More data for this Ligand-Target Pair
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: <50nMAssay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: 751nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
Ki: 1.40E+3nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: 1.40E+3nMAssay Description:The enzyme is commercially available human cathepsin L. The substrate is H-D-Val-Leu-Lys-AMC available from Bahcem. The assay buffer is 100 mM sodium...More data for this Ligand-Target Pair
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: 1.40E+3nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Ki: >1.00E+4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: 2.05E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: 2.20E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair
Ki: 2.20E+4nMpH: 7.0Assay Description:Standard assay conditions for the determination of kinetic constants used a fluorogenic peptide substrate, typically H-D-Ala-Leu-Lys-AMC, and were de...More data for this Ligand-Target Pair
BDBM123099(US10723709, Example 3 | US11312693, Example 3 | US...)
Ki: 2.20E+4nMAssay Description:The assay uses baculovirus-expressed human cathepsin S and the boc-Val-Leu-Lys-AMC fluorescent substrate available from Bachem in a 384 well plate fo...More data for this Ligand-Target Pair