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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Coagulation factor VII/Tissue factor
(Homo sapiens (Human))
Astellas Pharma
Curated by
ChEMBL
Ligand
BDBM31459
(CHEMBL224485 | substituted biphenyl derivative, 21)
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Affinity Data
IC50: 89nM
Assay Description:
Inhibition of human TF/FVIIa complex by chromogenic assay
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Coagulation factor VII
(Homo sapiens (Human))
Biocryst Pharmaceuticals
Ligand
BDBM31459
(CHEMBL224485 | substituted biphenyl derivative, 21)
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Affinity Data
IC50: 120nM
pH: 7.2 T: 2°C
Assay Description:
TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
PubMed
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Target
Serine protease 1
(Bos taurus (bovine))
Biocryst Pharmaceuticals
Ligand
BDBM31459
(CHEMBL224485 | substituted biphenyl derivative, 21)
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Affinity Data
IC50: 170nM
T: 2°C
Assay Description:
Trypsin assay reactions were performed in a mixture containing trypsin, and test compounds were added at varied concentrations. The reactions were in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Coagulation factor X
(Homo sapiens (Human))
Astellas Pharma
Curated by
ChEMBL
Ligand
BDBM31459
(CHEMBL224485 | substituted biphenyl derivative, 21)
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Affinity Data
IC50: 880nM
Assay Description:
Inhibition of human Fxa by chromogenic assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Prothrombin
(Homo sapiens (Human))
Biocryst Pharmaceuticals
Ligand
BDBM31459
(CHEMBL224485 | substituted biphenyl derivative, 21)
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Affinity Data
IC50: 6.40E+4nM
T: 2°C
Assay Description:
Thrombin assay reactions were performed in a reaction mixture containing thrombin, and test compounds were added at varied concentrations. The reacti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Coagulation factor X
(Homo sapiens (Human))
Astellas Pharma
Curated by
ChEMBL
Ligand
BDBM31459
(CHEMBL224485 | substituted biphenyl derivative, 21)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.03E+5nM
T: 2°C
Assay Description:
FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Biocryst Pharmaceuticals
Ligand
BDBM31459
(CHEMBL224485 | substituted biphenyl derivative, 21)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of human thrombin by chromogenic assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI