Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
27
hits in this display
Target
Beta-2 adrenergic receptor
(Rattus norvegicus)
Niigata College of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 339nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Albumin
(Homo sapiens (Human))
Molecular Discovery
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 354nM
Assay Description:
Binding affinity towards human serum albumin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.90E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Rattus norvegicus (Rat))
Niigata College of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.24E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Niigata College of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Canis familiaris)
Berlex Laboratories
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.00E+3nM
Assay Description:
Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine lung ti...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Canis familiaris)
Berlex Laboratories
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.00E+3nM
Assay Description:
In vitro Beta-2 adrenergic receptor affinity in partially purified membrane fractions from canine lung tissue using [SH]dihydroalprenolol (4.5 nM)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Canis familiaris)
Berlex Laboratories
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.20E+3nM
Assay Description:
Tested for Beta-2 adrenergic receptor selectivity in canine lung tissue in anesthetized dogs
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.20E+3nM
Assay Description:
Concentration effective against displacing [3H]dihydroalprenolol from beta adrenergic receptor from canine ventricular tissue
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.20E+3nM
Assay Description:
Tested for Beta adrenergic receptor binding inhibition from canine ventricular tissue, using [3H]dihydroalprenolol as the radioligand in anesthetized...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Berlex Laboratories
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.90E+3nM
Assay Description:
Tested for Beta-1 adrenergic receptor selectivity in canine cardiac tissue in anesthetized dogs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Berlex Laboratories
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.00E+3nM
Assay Description:
Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine ventricular...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Berlex Laboratories
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.00E+3nM
Assay Description:
In vitro Beta-1 adrenergic receptor affinity in partially purified membrane fractions from canine cardiac tissue using [SH]dihydroalprenolol (4.5 nM)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.35E+5nM
Assay Description:
Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S
(Homo sapiens (Human))
Chantest
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.93E+5nM
Assay Description:
Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunits
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human))
Jagiellonian University
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.02E+6nM
Assay Description:
Inhibition of L-type calcium channel measured using 2-electrode voltage-clamp in human embryonic kidney cells heterologically expressing alpha-1C sub...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 580nM
Assay Description:
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-like protein 11
(Homo sapiens (Human))
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >3.50E+5nM
Assay Description:
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
PCBioAssay
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
University of Nottingham
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 8.91E+3nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
TBA
Curated by
PDSP K
i
Database
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 141nM
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-1 adrenergic receptor
(Homo sapiens (Human))
Berlex Laboratories
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.70E+3nM
pH: 7.4 T: 2°C
Assay Description:
The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
Beta-2 adrenergic receptor
(BOVINE)
TBA
Curated by
ChEMBL
Ligand
BDBM25762
(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 580nM
Assay Description:
Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
KEGG
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI