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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  2.40nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  4.70nMAssay Description:Tested for inhibition of human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Bos taurus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50:  8.00E+4nMAssay Description:Tested for inhibition of Cathepsin D from bovineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of Angiotensin I converting enzyme from rabbit.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of renin from humanMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPepsin A(Porcine)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50012951(4-Cyclohexyl-2-hydroxy-3-[3-(1H-imidazol-4-yl)-2-(...)
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for inhibition of pepsin from porcineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed