Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341309
(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 23nM
Assay Description:
Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341309
(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 140nM
Assay Description:
Displacement of [3H]isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate/tert-butyl 4-(1-(4-(methyl...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341309
(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 84nM
Assay Description:
Agonist activity at rat GPR119 expressed in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341309
(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 7.30nM
Assay Description:
Agonist activity at human GPR119 receptor assessed as cAMP production by HTRF assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341309
(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 15nM
Assay Description:
Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Rattus norvegicus)
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341309
(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 83nM
Assay Description:
Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assay
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glucose-dependent insulinotropic receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50341309
(CHEMBL1766081 | isopropyl 4-(5-methyl-6-(2-methylp...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 14nM
Assay Description:
Agonist activity at GPR119 in human HEK293 cells assessed as increase in cAMP level after 16 hrs by beta-lactamase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI