Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380731((R)-6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d]...)
BDBM380617(6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d][1,2...)
IC50: 12nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380731((R)-6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d]...)
IC50: 12nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380731((R)-6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d]...)
IC50: 14nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380617(6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d][1,2...)
IC50: 15nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380617(6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d][1,2...)
IC50: 27nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380731((R)-6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d]...)
BDBM380617(6-(4-chlorophenyl)-5-(3,7-dimethyl-3H-benzo[d][1,2...)
IC50: 2.60E+3nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair