Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM380699(6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]triazolo...)
BDBM380699(6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]triazolo...)
IC50: <11nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380700((R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tria...)
IC50: 14nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380700((R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tria...)
IC50: 14nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380699(6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]triazolo...)
IC50: 19nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380700((R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tria...)
IC50: 25nMAssay Description:All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, plus 16 high- and...More data for this Ligand-Target Pair
BDBM380700((R)-6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]tria...)
BDBM380699(6-(4-chlorophenyl)-5-(3,8-dimethyl-[1,2,4]triazolo...)
IC50: 3.80E+3nMAssay Description:In order to assess bromodomain selectivity, we set up a binding assay using the bromodomain encoded by the CREBBP gene. Compounds were tested in the ...More data for this Ligand-Target Pair