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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Histamine H2 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50276073
(CHEMBL502339 | N1-[3-(1H-Imidazol-4-yl)propyl]-N2-...)
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Affinity Data
EC50: 109nM
Assay Description:
Activity at human recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50276073
(CHEMBL502339 | N1-[3-(1H-Imidazol-4-yl)propyl]-N2-...)
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Affinity Data
EC50: 21nM
Assay Description:
Activity at guinea pig recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H2 receptor
(Cavia porcellus (domestic guinea pig))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50276073
(CHEMBL502339 | N1-[3-(1H-Imidazol-4-yl)propyl]-N2-...)
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Copy InChI
Affinity Data
EC50: 38.0nM
Assay Description:
Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activity
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H4 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50276073
(CHEMBL502339 | N1-[3-(1H-Imidazol-4-yl)propyl]-N2-...)
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Affinity Data
EC50: 6.30nM
Assay Description:
Activity at human recombinant histamine H4 receptor-RGS4 fusion protein expressed in Sf9 cells coexpressing Galphai2 and G-beta-1-gamma-2 by steady-s...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histamine H3 receptor
(Homo sapiens (Human))
University Of Regensburg
Curated by
ChEMBL
Ligand
BDBM50276073
(CHEMBL502339 | N1-[3-(1H-Imidazol-4-yl)propyl]-N2-...)
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Affinity Data
EC50: 1.64nM
Assay Description:
Activity at human recombinant histamine H3 receptor expressed in Sf9 cells coexpressing Galphai, G-beta-1-gamma-2 and RGS4 by steady-state GTPase act...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI