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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
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Affinity Data
Ki: 3.98nM
Assay Description:
Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.98nM
Assay Description:
Displacement of [3H]GR113808 from human recombinant 5HT4c receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(Homo sapiens (Human))
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 31nM
Assay Description:
Displacement of [N-methyl-3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
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Copy InChI
Affinity Data
Ki: 2.51E+3nM
Assay Description:
Binding affinity to human recombinant 5HT3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Binding affinity at 5HT3 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
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Copy InChI
Affinity Data
EC50: 6.31nM
Assay Description:
Agonist activity at 5HT4 receptor in guinea pig colonic longitudinal muscle/myentric plexus assessed as contraction
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 13nM
Assay Description:
Induction of 5-HT4 receptor-mediated contraction in guinea pig longitudinal muscle myenteric plexus
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 4
(GUINEA PIG)
Theravance
Curated by
ChEMBL
Ligand
BDBM50240618
((2E)-2-[(5-methoxy-1H-indol-3-yl)methylene]-N-pent...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 6.31nM
Assay Description:
Agonist activity at 5HT4 receptor in guinea pig colon assessed as longitudinal muscle plexus contraction
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
ChEBI
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI