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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 17 hits in this display   

TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  2nMAssay Description:Inhibition of integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50:  21nMAssay Description:Inhibition of integrin alpha5beta1 receptor-mediated HEK293 cell adhesionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  76nMAssay Description:Inhibition of integrin alpha5beta1 receptor-mediated HEK293 cell adhesionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5(Homo sapiens (Human))
Shire Orphan Therapies

US Patent
LigandPNGBDBM141981(US8927534, 120)
Affinity DataIC50: <100nMpH: 9.6 T: 2°CAssay Description:Fibronectin was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates (Nalge Nu...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  351nMAssay Description:Inhibition of integrin alpha5beta1 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50:  614nMAssay Description:Inhibition of integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb(Homo sapiens (Human))
Shire Orphan Therapies

US Patent
LigandPNGBDBM141981(US8927534, 120)
Affinity DataIC50: >1.00E+3nMpH: 9.6 T: 2°CAssay Description:Fibrinogen was diluted with coating buffer (15 mM Na2CO3, 35 mM NaHCO3, pH 9.6) and coated with 100 uL/well to Nunc-Immuno maxisorp plates over night...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  6.91E+3nMAssay Description:Inhibition of integrin alpha5beta1 receptor-mediated HEK293 cell adhesionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of integrin alpha5beta5 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  1.66E+4nMAssay Description:Inhibition of integrin alpha5beta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  7.17E+4nMAssay Description:Inhibition of integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423732(CHEMBL590389)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Jerini

Curated by ChEMBL
LigandPNGBDBM50423731(CHEMBL590622)
Affinity DataIC50:  1.59E+5nMAssay Description:Inhibition of integrin alpha2bbeta3 receptor by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed