Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50392774(CHEMBL2151149)Copy SMILESCopy InChI

Affinity DataIC50:  110nMAssay Description:Inhibition of BACEMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBeta-secretase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50392774(CHEMBL2151149)Copy SMILESCopy InChI

Affinity DataIC50:  370nMAssay Description:Inhibition of BACE by cells based assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50392774(CHEMBL2151149)Copy SMILESCopy InChI

Affinity DataIC50:  700nMAssay Description:Inhibition of Cathepsin D (unknown origin) by FRET assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI