Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]-raclopride from D2 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  4.13E+3nMAssay Description:Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(RAT)
Universidad De Valencia

Curated by ChEMBL
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataKi:  4.14E+3nMAssay Description:Displacement of [3H]-SCH23390 from D1 receptor of Wistar rat striatal membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA polymerase(Vaccinia virus (strain WR))
University of Pennsylvania

US Patent
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataIC50:  5.40E+3nMpH: 7.4 T: 2°CAssay Description:A rapid plate DNA synthesis assay was performed using optimized conditions. Briefly, a 1.2:1 ratio of a 20-mer oligonucleotide primer (5′-GCGAA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataIC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM69679(Dimethyl-(2-phenanthro[3,4-d][1,3]dioxol-5-yl-ethy...)
Affinity DataEC50:  2.59E+4nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PCBioAssay