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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10149(CHEMBL168640 | lysine sulfonamide analogue 13 | ly...)
Affinity DataIC50:  0.5nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482335(MK-8122 | MX-100 | PL 100 (PHARMACEUTICAL) | PL-10...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [501-599](Human immunodeficiency virus type 1)
Ambrilia Biopharma

LigandPNGBDBM10149(CHEMBL168640 | lysine sulfonamide analogue 13 | ly...)
Affinity DataIC50:  13nMpH: 4.7 T: 2°CAssay Description:HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Ambrilia Biopharma

Curated by ChEMBL
LigandPNGBDBM10149(CHEMBL168640 | lysine sulfonamide analogue 13 | ly...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed