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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Dimer of Gag-Pol polyprotein [501-599]
(Human immunodeficiency virus type 1)
Ambrilia Biopharma
Ligand
BDBM10149
(CHEMBL168640 | lysine sulfonamide analogue 13 | ly...)
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Affinity Data
IC50: 0.5nM
pH: 4.7 T: 2°C
Assay Description:
HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Protease
(Human immunodeficiency virus 1 (HIV-1))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50482335
(MK-8122 | MX-100 | PL 100 (PHARMACEUTICAL) | PL-10...)
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Affinity Data
IC50: 0.5nM
Assay Description:
Inhibition of HIV1 protease
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Dimer of Gag-Pol polyprotein [501-599]
(Human immunodeficiency virus type 1)
Ambrilia Biopharma
Ligand
BDBM10149
(CHEMBL168640 | lysine sulfonamide analogue 13 | ly...)
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Copy InChI
Affinity Data
IC50: 13nM
pH: 4.7 T: 2°C
Assay Description:
HIV-1 protease activity was measured by a continuous fluorometric assay. The proteolytic activity can be monitored by the increase in fluorescence in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cathepsin D
(Homo sapiens (Human))
Ambrilia Biopharma
Curated by
ChEMBL
Ligand
BDBM10149
(CHEMBL168640 | lysine sulfonamide analogue 13 | ly...)
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Affinity Data
IC50: >5.00E+4nM
Assay Description:
Inhibition of human cathepsin D
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI