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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
345
hits in this display
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of recombinant GST-tagged HER2 (unknown origin) (catalytic domain 675 to 1225) residues expressed in baculovirus-infected Sf9 cells assess...
More data for this Ligand-Target Pair
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
IC50: 10nM
Assay Description:
Inhibition of ERBB2 (unknown orgin)
More data for this Ligand-Target Pair
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of recombinant HER2 (675 to 1255) (unknown origin) expressed in baculovirus infected Sf9 insect cells using poly-Glu-Tyr as substrate incu...
More data for this Ligand-Target Pair
Target Info
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Inhibition of recombinant human GST-fused HER2 (675 to 1255 residues) assessed as phosphotyrosine formation using poly(Glu:Tyr, 4:1) as substrate and...
More data for this Ligand-Target Pair
Target Info
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
Inhibition of HER2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Inhibition of ERBB2 (unknown orgin) by cell-based assay
More data for this Ligand-Target Pair
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
IC50: 6.40E+3nM
Assay Description:
Inhibition of recombinant human GST-fused EGFR (668 to 1211 residues) assessed as phosphotyrosine formation using poly(Glu:Tyr, 4:1) as substrate and...
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
IC50: 6.40E+3nM
Assay Description:
Inhibition of human recombinant EGFR (668 to 1211) expressed in baculovirus infected Sf9 insect cells using poly-Glu-Tyr as substrate incubated for 5...
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor [G719C]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 10nM
pH: 7.4 T: 2°C
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
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Target
Cyclin-dependent kinase 19
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 1.10E+3nM
pH: 7.4 T: 2°C
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
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Target
Cyclin-dependent kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 2.30E+3nM
pH: 7.4 T: 2°C
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.00E+3nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor [1-999,L858R]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 1.10E+5nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.00E+3nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 43nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
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MMDB
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Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 840nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 42nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 17nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 720nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.80E+3nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 560nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 36nM
Assay Description:
Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...
More data for this Ligand-Target Pair
Target Info
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Target
Ferrochelatase, mitochondrial [R115L]
(Homo sapiens (Human))
Technical University of Munich
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 2.30E+4nM
Assay Description:
Briefly, 5 mg of a protein mixture of the four cell lines or a single cell line were incubated with compound dilution series in DMSO (3 nM, 10 nM, 30...
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA kinase domain
More data for this Ligand-Target Pair
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D,T670I) kinase domain
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Target
Interleukin-1 receptor-associated kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IRAK3 kinase domain
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET(M918T) kinase domain
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Target
Protein kinase C eta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCH kinase domain
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 1.80E+3nM
Assay Description:
Binding constant for EGFR(L747-S752del, P753S) kinase domain
More data for this Ligand-Target Pair
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 110nM
Assay Description:
Binding constant for EGFR(L858R) kinase domain
More data for this Ligand-Target Pair
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(M351T) kinase domain
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Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA2(Kin.Dom.2 - C-terminal) kinase domain
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Target
cGMP-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG1 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(D835H) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA6(Kin.Dom.1 - C-terminal) kinase domain
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Target
Myotonin-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK kinase domain
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Target Info
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Target
Death-associated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DAPK3 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Aurora kinase B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKB kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR3(G697C) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA1(Kin.Dom.2 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D,V654A) kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(V559D) kinase domain
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(T315I) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF(V600E) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(H396P) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 10nM
Assay Description:
Binding constant for EGFR(G719C) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(ITD) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CHEK1 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 42nM
Assay Description:
Binding constant for EGFR kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(D835Y) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 560nM
Assay Description:
Binding constant for EGFR(L747-T751del,Sins) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 1.00E+3nM
Assay Description:
Binding constant for EGFR(S752-I759del) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(E255K) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.1 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(Q252H) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase D2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD2 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1(Y253F) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 17nM
Assay Description:
Binding constant for EGFR(G719S) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.1 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 720nM
Assay Description:
Binding constant for EGFR(L747-E749del, A750P) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 36nM
Assay Description:
Binding constant for EGFR(L861Q) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Atypical kinase COQ8B, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length ADCK4
More data for this Ligand-Target Pair
Target Info
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Target
AP2-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AAK1 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase 17B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DRAK2
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Calcium/calmodulin-dependent protein kinase type 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CAMK1
More data for this Ligand-Target Pair
Target Info
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Target
Ankyrin repeat and protein kinase domain-containing protein 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ANKK1 kinase domain
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Target Info
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Target
Protein kinase C delta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCD kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Discoidin domain-containing receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DDR2 kinase domain
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
5'-AMP-activated protein kinase catalytic subunit alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AMPK-alpha2 kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Dual specificity protein kinase CLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CLK1
More data for this Ligand-Target Pair
Target Info
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Target
cAMP-dependent protein kinase catalytic subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PKAC-alpha kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K4 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Mitogen-activated protein kinase kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K5 kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
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Target
Ribosomal protein S6 kinase alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA1(Kin.Dom.1 - N-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase MRCK beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKB kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Cyclin-dependent kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK7
More data for this Ligand-Target Pair
Target Info
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Target
Cyclin-dependent kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK9
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase Nek5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK5 kinase domain
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Target Info
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Target
Ribosomal protein S6 kinase alpha-4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA4(Kin.Dom.1 - C-terminal) kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
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Target
Ephrin type-A receptor 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA5 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA6 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Calcium/calmodulin-dependent protein kinase type II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2A kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
MAP/microtubule affinity-regulating kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK4 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Citron Rho-interacting kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CIT kinase domain
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Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LCK kinase domain
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Target Info
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Target
Tyrosine-protein kinase ITK/TSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ITK kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK1(Kin.Dom.1/JH2 - pseudokinase) kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
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Target
ALK tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ALK kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIK3CA kinase domain
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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Target
Serine/threonine-protein kinase SIK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SNF1LK kinase domain
More data for this Ligand-Target Pair
Target Info
NCI pathway
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Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRC kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase Srms
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SRMS kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Mitogen-activated protein kinase kinase kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K5 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Tsinghua University
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: 2.00E+3nM
Assay Description:
Binding constant for EGFR(E746-A750del) kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ephrin type-A receptor 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA7 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase ABL2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL2 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Cyclin-dependent kinase 11B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L1 kinase domain
More data for this Ligand-Target Pair
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Target
Serine/threonine-protein kinase 32B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length YANK2
More data for this Ligand-Target Pair
Target Info
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Target
Dual specificity protein kinase CLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK2 kinase domain
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Target
Protein kinase C theta type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCQ kinase domain
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Target
Leukocyte tyrosine kinase receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for LTK kinase domain
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Target
Tyrosine-protein kinase Lyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for LYN kinase domain
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Target
Cyclin-dependent kinase 19
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 1.10E+3nM
Assay Description:
Binding constant for CDK11 kinase domain
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Target
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM1 kinase domain
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Target
Serine/threonine-protein kinase pim-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM2 kinase domain
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Target
Epithelial discoidin domain-containing receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DDR1 kinase domain
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Target
Myosin-IIIa
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3A kinase domain
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Target
Myosin-IIIb
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MYO3B kinase domain
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Target
Mitogen-activated protein kinase kinase kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K1 kinase domain
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Target
Ephrin type-B receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB2 kinase domain
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Target
Tyrosine-protein kinase Fyn
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for FYN kinase domain
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Target
Casein kinase II subunit alpha'
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK2A2
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Target
Tyrosine-protein kinase ABL1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ABL1 kinase domain
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Target
Serine/threonine-protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MST1
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Target
Serine/threonine-protein kinase B-raf
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRAF kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MEK1
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for KIT(D816V) kinase domain
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK2
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Target
Cyclin-dependent kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK3
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Target
Cyclin-dependent kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CDK5
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Target
MAP/microtubule affinity-regulating kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MARK3
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Target
Insulin receptor-related protein
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for INSRR kinase domain
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Target
Insulin receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for INSR kinase domain
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Target
Activin receptor type-2B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2B kinase domain
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Target
Tyrosine-protein kinase receptor Tie-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE1 kinase domain
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Target
Aurora kinase C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length AURKC
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Target
Cytoplasmic tyrosine-protein kinase BMX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length BMX
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Target
Serine/threonine-protein kinase 26
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MST4
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Target
Cyclin-dependent kinase 17
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PCTK2
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Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TIE2 kinase domain
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Target
Serine/threonine-protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MST2 kinase domain
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Target
Serine/threonine-protein kinase RIO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length RIOK3
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Target
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DYRK1B
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Mitogen-activated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length ERK1
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Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length ERK2
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Target
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PIP5K1A
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MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK2 kinase domain
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Target
Cyclin-dependent kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 2.30E+3nM
Assay Description:
Binding constant for CDK8 kinase domain
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Target
Myosin light chain kinase, smooth muscle
(Gallus gallus (chicken))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLCK kinase domain
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Calcium/calmodulin-dependent protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMKK2 kinase domain
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Target
Mitogen-activated protein kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK4 kinase domain
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Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK3 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK2 kinase domain
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Target
Serine/threonine-protein kinase STK11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length LKB1
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Target
Serine/threonine-protein kinase MRCK alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MRCKA kinase domain
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Target
Serine/threonine-protein kinase BRSK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BRSK1 kinase domain
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Calcium/calmodulin-dependent protein kinase type 1D
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1D kinase domain
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Target
Serine/threonine-protein kinase SIK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length SNF1LK2
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Target
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PKMYT1 kinase domain
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Target
Serine/threonine-protein kinase receptor R3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVRL1 kinase domain
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Target
Serine/threonine-protein kinase 24
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MST3 kinase domain
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Target
Macrophage colony-stimulating factor 1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSF1R kinase domain
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Target
Non-receptor tyrosine-protein kinase TNK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length TNK1
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Target
Serine/threonine-protein kinase TNNI3K
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length TNNI3K
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Target
MAP kinase-activated protein kinase 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAPKAPK5 kinase domain
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RAF1 kinase domain
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Target
eIF-2-alpha kinase GCN2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for GCN2(Kin.Dom.2,S808G) kinase domain
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Target
Serine/threonine-protein kinase tousled-like 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK2 kinase domain
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Target
Mitogen-activated protein kinase 7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK5 kinase domain
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Target
Death-associated protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DAPK1 kinase domain
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Target
Serine/threonine-protein kinase 36
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for STK36 kinase domain
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Target
Serine/threonine-protein kinase DCLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL1 kinase domain
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Target
Serine/threonine-protein kinase Nek1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK1 kinase domain
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Target
Serine/threonine-protein kinase PAK 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK6 kinase domain
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Target
STE20-like serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SLK kinase domain
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Target
Ribosomal protein S6 kinase alpha-5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA5(Kin.Dom.1 - C-terminal) kinase domain
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Target
cAMP-dependent protein kinase catalytic subunit PRKX
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PRKX
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Target
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PTK2B
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Target
Serine/threonine-protein kinase tousled-like 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TLK1 kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type II subunit gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2G kinase domain
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Target
Muscle, skeletal receptor tyrosine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MUSK kinase domain
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Target
cAMP-dependent protein kinase catalytic subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PKAC-beta
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Target
TRAF2 and NCK-interacting protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNIK kinase domain
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Target
Casein kinase I isoform epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1E
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Target
Casein kinase I isoform gamma-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1G3
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Target
Casein kinase I isoform delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1D
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Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PIP5K2B
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Target
Tyrosine-protein kinase JAK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK2(Kin.Dom.2/JH1 - catalytic) kinase domain
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Target
Tyrosine-protein kinase Fes/Fps
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FES kinase domain
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Target
Fibroblast growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR1 kinase domain
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Target
Activated CDC42 kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TNK2 kinase domain
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Target
Non-receptor tyrosine-protein kinase TYK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TYK2(Kin.Dom.2/JH1 - catalytic) kinase domain
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Target
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TYRO3 kinase domain
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Target Info
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Target
High affinity nerve growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKA kinase domain
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Target
Ephrin type-B receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB3 kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type 1G
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK1G kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase PAK 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK1 kinase domain
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Target
Myosin light chain kinase 2, skeletal/cardiac muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK2 kinase domain
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TGFBR1 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ephrin type-A receptor 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA8 kinase domain
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 43nM
Assay Description:
Binding constant for ERBB2 kinase domain
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Target
Cyclin-dependent kinase 18 [3-474]
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PCTK3
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Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PDPK1
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase JAK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JAK3(Kin.Dom.2/JH1 - catalytic) kinase domain
More data for this Ligand-Target Pair
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Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for JNK3 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase Fer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FER kinase domain
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Target
Serine/threonine-protein kinase pim-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PIM3 kinase domain
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Target
Serine/threonine-protein kinase 38-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NDR2 kinase domain
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Target
Myosin light chain kinase family member 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for SgK085 kinase domain
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Target
BDNF/NT-3 growth factors receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKB kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Activin receptor type-1B
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR1B kinase domain
More data for this Ligand-Target Pair
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Target
NT-3 growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TRKC kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase receptor UFO
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AXL kinase domain
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Target
BMP-2-inducible protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for BIKE kinase domain
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Target
Serine/threonine-protein kinase 10
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LOK kinase domain
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Target
Mitogen-activated protein kinase kinase kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP4K3 kinase domain
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Target
Serine/threonine-protein kinase Nek2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK2 kinase domain
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Target
Ephrin type-B receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB4 kinase domain
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Target
Serine/threonine-protein kinase 33
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length STK33
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Target
TGF-beta receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TGFBR2 kinase domain
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Target
SRSF protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length SRPK1
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Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT4 kinase domain
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Target
Cyclin-G-associated kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for GAK kinase domain
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Target
Serine/threonine-protein kinase DCLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL3 kinase domain
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Target
Fibroblast growth factor receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR2 kinase domain
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Fibroblast growth factor receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR4 kinase domain
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Target
Ribosomal protein S6 kinase alpha-6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA6(Kin.Dom.2 - N-terminal) kinase domain
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Target
Dual specificity testis-specific protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TESK1 kinase domain
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Target
Fibroblast growth factor receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGFR3 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for MLK1 kinase domain
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Target
Activin receptor type-2A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR2A kinase domain
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Target
Death-associated protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DAPK2
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Target
Tubulin alpha-1A chain
(Rattus norvegicus)
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 260nM
Assay Description:
Binding constant for ERBB4 kinase domain
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Target
Serine/threonine-protein kinase BRSK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length BRSK2
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Target
Tyrosine-protein kinase BTK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length BTK
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Target
Serine/threonine-protein kinase PLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK4 kinase domain
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Target Info
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Target
Testis-specific serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length TSSK1
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Target
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PHKG2 kinase domain
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Target
Casein kinase I isoform alpha-like
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1A1L
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Target
Mitogen-activated protein kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK3 kinase domain
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Target
Tyrosine-protein kinase FRK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FRK kinase domain
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Target
Serine/threonine-protein kinase PAK 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PAK3
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Target
cGMP-dependent protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKG2 kinase domain
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Target
Serine/threonine-protein kinase MRCK gamma
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DMPK2 kinase domain
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Target
Serine/threonine-protein kinase LATS1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LATS1 kinase domain
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Target
Hepatocyte growth factor receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MET kinase domain
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Target
MAP kinase-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 840nM
Assay Description:
Binding constant for MKNK2 kinase domain
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Target
Mitogen-activated protein kinase kinase kinase 20
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAK kinase domain
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Target
Ephrin type-A receptor 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA3 kinase domain
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Target
Dual specificity protein kinase TTK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TTK kinase domain
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Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for VEGFR2 kinase domain
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Target
Serine/threonine-protein kinase PAK 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK2 kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type II subunit beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2B kinase domain
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Target
NUAK family SNF1-like kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for SNARK kinase domain
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Target
Serine/threonine-protein kinase Nek6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK6 kinase domain
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Target
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK4 kinase domain
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Target
Interferon-induced, double-stranded RNA-activated protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKR kinase domain
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Target
MAP kinase-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MKNK1
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Target
Cyclin-dependent kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PFTK1
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Target
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length PHKG1
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Target
Serine/threonine-protein kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for STK16 kinase domain
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Target
Tyrosine-protein kinase SYK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for SYK kinase domain
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Target
Tyrosine-protein kinase Tec
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for TEC kinase domain
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Target
SRSF protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length SRPK2
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Target
Wee1-like protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for WEE1 kinase domain
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Target
Tyrosine-protein kinase Blk
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BLK kinase domain
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Target
Bone morphogenetic protein receptor type-1A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR1A kinase domain
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Target
Bone morphogenetic protein receptor type-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for BMPR2 kinase domain
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Target
Serine/threonine-protein kinase Nek9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for NEK9 kinase domain
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Target
Serine/threonine-protein kinase N1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PKN1 kinase domain
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Target
Serine/threonine-protein kinase N2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for PKN2 kinase domain
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Target
Atypical kinase COQ8A, mitochondrial
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ADCK3 kinase domain
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Target
Mitogen-activated protein kinase 15
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ERK8 kinase domain
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Target
Activin receptor type-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for ACVR1 kinase domain
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Target
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT2 kinase domain
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Target
RAC-gamma serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT3 kinase domain
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Target
Serine/threonine-protein kinase RIO1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length RIOK1
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Target
Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length GSK3A
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length GSK3B
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Target
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length IKK-epsilon
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Target
Serine/threonine-protein kinase NLK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length NLK
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Target
Casein kinase II subunit alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK2A1
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Target
Dual specificity protein kinase CLK4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CLK4 kinase domain
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Target
Focal adhesion kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PTK2 kinase domain
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Target Info
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Target
Protein-tyrosine kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PTK6 kinase domain
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Target
Serine/threonine-protein kinase MARK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK1 kinase domain
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Target
Dual specificity protein kinase CLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CLK3
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Target
NUAK family SNF1-like kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ARK5 kinase domain
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Target
Serine/threonine-protein kinase LATS2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for LATS2 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length JNK1
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase Yes
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YES kinase domain
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Target
Serine/threonine-protein kinase 25
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YSK1 kinase domain
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Target
Receptor-interacting serine/threonine-protein kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK2 kinase domain
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Target
Tyrosine-protein kinase Fgr
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FGR kinase domain
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Target
Serine/threonine-protein kinase PLK1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK1 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase DCLK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DCAMKL2 kinase domain
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Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RET kinase domain
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length p38-alpha
More data for this Ligand-Target Pair
Target Info
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Target
Mitogen-activated protein kinase 11
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length p38-beta
More data for this Ligand-Target Pair
Target Info
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AKT1 kinase domain
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Target
Serine/threonine-protein kinase MARK2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MARK2 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PLK3 kinase domain
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Target Info
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Target
Protein kinase C epsilon type
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKCE kinase domain
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Target
Casein kinase I isoform gamma-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSNK1G2
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase CSK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length CSK
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Target Info
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Target
Calcium/calmodulin-dependent protein kinase type IV
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK4 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Calcium/calmodulin-dependent protein kinase kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMKK1 kinase domain
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Target Info
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Target
Aurora kinase A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AURKA kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Ephrin type-A receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA1 kinase domain
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Target
Ephrin type-A receptor 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA2 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT1 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Mitogen-activated protein kinase 12
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length p38-gamma
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase HCK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for HCK kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Dual specificity mitogen-activated protein kinase kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MEK2
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Target Info
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Target
Dual specificity mitogen-activated protein kinase kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MEK3
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Target
Serine/threonine-protein kinase D1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD1 kinase domain
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Target
Insulin-like growth factor 1 receptor
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for IGF1R kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK4 kinase domain
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Target
Calcium/calmodulin-dependent protein kinase type II subunit delta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CAMK2D kinase domain
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Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PDGFRA kinase domain
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Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PDGFRB kinase domain
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Target Info
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Target
Casein kinase I isoform gamma-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CSNK1G1 kinase domain
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Target
Serine/threonine-protein kinase 32C
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for YANK3 kinase domain
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Target
Ephrin type-A receptor 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHA4 kinase domain
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Target Info
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Target
Ribosomal protein S6 kinase alpha-2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA2(Kin.Dom.2 - C-terminal) kinase domain
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Target
Serine/threonine-protein kinase PAK 5
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PAK7/PAK5 kinase domain
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Target
Tyrosine-protein kinase ZAP-70
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ZAP70 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Maternal embryonic leucine zipper kinase
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length MELK
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Target
Serine/threonine-protein kinase Nek7
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length NEK7
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Target Info
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Target
Ephrin type-B receptor 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for EPHB1 kinase domain
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Target
Receptor-interacting serine/threonine-protein kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RIPK1 kinase domain
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for FLT3(N841I) kinase domain
More data for this Ligand-Target Pair
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Target
Serine/threonine-protein kinase D3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PRKD3 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Serine/threonine-protein kinase 17A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for DRAK1 kinase domain
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Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length JNK2
More data for this Ligand-Target Pair
Target Info
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Target
LIM domain kinase 1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length LIMK1
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Target
LIM domain kinase 2
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length LIMK2
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Target Info
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Target
Mitogen-activated protein kinase kinase kinase 4
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MAP3K4 kinase domain
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Target
5'-AMP-activated protein kinase catalytic subunit alpha-1
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for AMPK-alpha1 kinase domain
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Target
Cyclin-dependent kinase 16
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for PCTK1 kinase domain
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Target
Dual specificity mitogen-activated protein kinase kinase 6
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MEK6 kinase domain
More data for this Ligand-Target Pair
Target Info
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Target
Tyrosine-protein kinase Mer
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MERTK kinase domain
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Target
Proto-oncogene tyrosine-protein kinase ROS
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for ROS1 kinase domain
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Target
Tyrosine-protein kinase TXK
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for TXK kinase domain
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Target
Myosin light chain kinase, smooth muscle
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for MYLK kinase domain
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Target
Cyclin-dependent kinase 11A
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for CDC2L2 kinase domain
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Target
Death-associated protein kinase 3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for full-length DLK
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Target
Ribosomal protein S6 kinase alpha-3
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding constant for RPS6KA3(Kin.Dom.1 - N-terminal) kinase domain
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Ambit Biosciences
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: >1.00E+4nM
Assay Description:
Binding affinity to human KIT incubated for 1 hr by kinase binding assay
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Target
Cyclin-dependent kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 2.30E+3nM
Assay Description:
Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay
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PubMed
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 43nM
Assay Description:
Binding affinity to wild-type partial length human ERRB2 (K646 to V1225 residues) expressed in mammalian expression system by Kinomescan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 8
(Homo sapiens (Human))
Ambit Biosciences
Curated by
PubChem BioAssay
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
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Affinity Data
Kd: 2.30E+3nM
Assay Description:
Binding affinity to wild-type partial length human CDK8 (M1 to T360 residues) expressed in bacterial expression system by Kinomescan assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
Arromax Pharmatech
Curated by
ChEMBL
Ligand
BDBM31340
(2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 43nM
Assay Description:
Binding affinity to wild-type partial length human ERRB2 (K646 to V1225 residues) expressed in mammalian expression system by Kinomescan assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
In Depth
Details
Article
PubMed
Copy BDB DOI
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