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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
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Affinity Data
Ki: 1.00E+8nM
Assay Description:
Inhibition of 5HT6 receptor
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
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Affinity Data
Ki: 1.00E+8nM
Assay Description:
Inhibition of 5HT2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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B.MOAD
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Target
Histamine H2 receptor
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
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Affinity Data
Ki: 1.00E+8nM
Assay Description:
Inhibition of histamine H2 receptor
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 3A
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+8nM
Assay Description:
Inhibition of 5HT3 receptor
More data for this Ligand-Target Pair
Target Info
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Target
P2X purinoceptor 3
(RAT)
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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PubMed
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Target
P2X purinoceptor 3
(RAT)
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Antagonist activity at rat recombinant P2X3 receptor expressed in CHO cells by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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CHEMBL
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Target
P2X purinoceptor 3
(RAT)
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10nM
Assay Description:
Antagonist activity at rat P2X3 receptor expressed in CHO cells by FLIPR
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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Target
P2X purinoceptor 3
(Homo sapiens (Human))
Gedeon Richter
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
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Affinity Data
IC50: 20nM
Assay Description:
Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
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Target
P2X purinoceptor 3
(Homo sapiens (Human))
Gedeon Richter
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 20nM
Assay Description:
Antagonist activity at human recombinant P2X3 receptor expressed in HEK293-Tet-on cells assessed as alpha,beta-methylene-ATP-stimulated Ca2+ influx b...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
P2X purinoceptor 2
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
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Affinity Data
IC50: 39.8nM
Assay Description:
Antagonist activity at human P2X2/3 receptor expressed in 1321n1c cells by FLIPR
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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Target
P2X purinoceptor 2
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 39.8nM
Assay Description:
Antagonist activity at human P2X2/3 receptor expressed in 1321n1c cells by FLIPR
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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CHEMBL
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PC sid
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PubMed
Copy BDB DOI
Target
P2X purinoceptor 2
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 79nM
Assay Description:
Inhibition of P2X2 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
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CHEMBL
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Target
P2X purinoceptor 4
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of P2X4 receptor
More data for this Ligand-Target Pair
Target Info
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KEGG
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Target
P2X purinoceptor 1
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of P2X1 receptor
More data for this Ligand-Target Pair
Target Info
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Target
P2X purinoceptor 7
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of P2X7 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
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CHEMBL
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Target
P2X purinoceptor 2
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of P2X2 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
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CHEMBL
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Target
P2X purinoceptor 5
(Homo sapiens (Human))
Roche Palo Alto
Curated by
ChEMBL
Ligand
BDBM50257636
(5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of P2X5 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
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Ligand Info
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CHEMBL
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PC sid
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In Depth
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PubMed
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