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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Prothrombin
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13580
(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
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Affinity Data
Ki: 270nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Serine protease 1
(Bos taurus (bovine))
F. Hoffmann-La Roche
Ligand
BDBM13580
(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
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Affinity Data
Ki: 580nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Coagulation factor VII
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13580
(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
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Affinity Data
Ki: 1.00E+3nM ΔG°: -33.9kJ/mole
pH: 7.8 T: 2°C
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Coagulation factor X
(Homo sapiens (Human))
F. Hoffmann-La Roche
Ligand
BDBM13580
(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
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Affinity Data
Ki: 1.20E+3nM
Assay Description:
The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mas-related G-protein coupled receptor member X1
(Homo sapiens (Human))
Eisai
Curated by
ChEMBL
Ligand
BDBM13580
(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
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Affinity Data
EC50: 510nM
Assay Description:
Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI