Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetProthrombin(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  270nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Bos taurus (bovine))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  580nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  1.00E+3nM ΔG°:  -33.9kJ/molepH: 7.8 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataKi:  1.20E+3nMAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMas-related G-protein coupled receptor member X1(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM13580(4-({[4-(benzyloxy)-3-methoxyphenyl]methyl}amino)be...)
Affinity DataEC50:  510nMAssay Description:Agonist activity at human MrgprX1 expressed in HEK293 cells incubated for 2 mins by Fluo4AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed