Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 29 hits in this display
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
IC50: 4.90E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH using dextromethorphan as substrate measured within 2.5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes in presence of NADPH using amodiaquine as substrate measured within 2.5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes in presence of NADPH using diclofenac as substrate measured within 2.5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
IC50: >5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH using midazolam as substrate measured within 2.5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
IC50: >5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH using mephenytoin as substrate measured within 2.5 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
Kd: >1.00E+4nMAssay Description:Binding affinity to BRD4 BD1 (unknown origin) assessed as dissociation constant by SYPRO orange dye based differential scanning fluorimetryMore data for this Ligand-Target Pair
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)
BDBM50183449(CHEMBL3823101 | US11773085, Compound B23)