Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50244023(CHEMBL4097617)Copy SMILESCopy InChI

Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHOA12 cells assessed as induction of Ca2+ mobilization by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))TBA

LigandBDBM50244023(CHEMBL4097617)Copy SMILESCopy InChI

Affinity DataEC50: >5.00E+4nMAssay Description:Transactivation of PPARgamma (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails PubMed
Copy BDB DOI

TargetFree fatty acid receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL

LigandBDBM50244023(CHEMBL4097617)Copy SMILESCopy InChI

Affinity DataEC50:  1.40E+3nMAssay Description:Positive allosteric modulation of human GPR40 expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails PubMed
Copy BDB DOI