Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Weill Cornell Medical College

LigandBDBM119877(SL809 | US9073941, 502)Copy SMILESCopy InChI

Affinity DataKi:  93nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

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In DepthDetails ArticlePubMed
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TargetPrephenate dehydrogenase(Mycobacterium tuberculosis H37Rv)
Weill Cornell Medical College

LigandBDBM119877(SL809 | US9073941, 502)Copy SMILESCopy InChI

Affinity DataKi:  155nMAssay Description:IC50 values were determined with serial dilutions (from 100 to 0.1 uM) of inhibitors by a spectrophotometric assay with DTNB, lipoamide, and NADH or ...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDihydrolipoyl dehydrogenase(Mycobacterium tuberculosis)
Academia Sinica

US Patent

LigandBDBM119877(SL809 | US9073941, 502)Copy SMILESCopy InChI

Affinity DataIC50:  840nMpH: 7.0Assay Description:The assay was performed in a manner similar to that described in Bryk et al., Biochemistry (2010) 49:1616-1627 and modified for an online robotics sc...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI