Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 31 hits in this display
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Ki: 22nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer by topcount assayMore data for this Ligand-Target Pair
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Ki: 350nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer by topcount assayMore data for this Ligand-Target Pair
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Ki: 383nMAssay Description:Displacement of [3H]-pentazocine from sigma1 receptor (unknown origin) after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Ki: 720nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Ki: 1.24E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Ki: 2.75E+3nMAssay Description:Displacement of [3H]-DTG from sigma 2 receptor (unknown origin) measured after 90 mins by microbeta counting analysisMore data for this Ligand-Target Pair
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
Ki: 3.70E+3nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
EC50: >1.00E+4nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter® βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 R...More data for this Ligand-Target Pair
D(3) dopamine receptor(Homo sapiens)The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)
BDBM50527972(CHEMBL4476784 | US11634404, Compound 1)