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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Coagulation factor VII
(Homo sapiens (Human))
Biocryst Pharmaceuticals
Ligand
BDBM31461
(substituted biphenyl derivative, 24)
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Affinity Data
IC50: 30nM
pH: 7.2 T: 2°C
Assay Description:
TF-FVIIa assay reactions were performed in a mixture containing FVIIa , lapidated tissue factor, in an assay buffer in the presence of test compounds...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Serine protease 1
(Bos taurus (bovine))
Biocryst Pharmaceuticals
Ligand
BDBM31461
(substituted biphenyl derivative, 24)
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Affinity Data
IC50: 820nM
T: 2°C
Assay Description:
Trypsin assay reactions were performed in a mixture containing trypsin, and test compounds were added at varied concentrations. The reactions were in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Coagulation factor X
(Homo sapiens (Human))
Biocryst Pharmaceuticals
Ligand
BDBM31461
(substituted biphenyl derivative, 24)
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Affinity Data
IC50: 6.63E+3nM
T: 2°C
Assay Description:
FXa assay reactions were performed in a reaction mixture containing FXa, and test compounds were added at varied concentrations and reactions were in...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Plasminogen
(Homo sapiens (Human))
Biocryst Pharmaceuticals
Ligand
BDBM31461
(substituted biphenyl derivative, 24)
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Affinity Data
IC50: 1.44E+4nM
T: 2°C
Assay Description:
The assay is an amidolytic assay based upon the absorbance of derivatized thiols from the hydrolysis of Z-Lys-SBzl (Bachem) in the presence of 5,5-Di...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Prothrombin
(Homo sapiens (Human))
Biocryst Pharmaceuticals
Ligand
BDBM31461
(substituted biphenyl derivative, 24)
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Affinity Data
IC50: 1.49E+4nM
T: 2°C
Assay Description:
Thrombin assay reactions were performed in a reaction mixture containing thrombin, and test compounds were added at varied concentrations. The reacti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI