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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Carbonic anhydrase 2
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 5nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 4
(Bos taurus (bovine))
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 39nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Carbonic anhydrase 1
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 50nM
Assay Description:
Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 78nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 78nM
Assay Description:
Inhibition of MMP9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 83nM
Assay Description:
Inhibition of MMP2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pomona College
Curated by
ChEMBL
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Copy InChI
Affinity Data
Ki: 84nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase ColG
(Clostridium histolyticum)
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 95nM
Assay Description:
The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neutrophil collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: 123nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Universita Degli Studi
Ligand
BDBM11346
(Hydroxamate 27 | N-hydroxy-2-[(4-methoxybenzene)su...)
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Affinity Data
Ki: >200nM
Assay Description:
Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI