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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
17
hits in this display
Target
Histone deacetylase 8
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of C-terminal GST-tagged full length human HDAC8 (518 to end residues) expressed in baculovirus expression system using Ac-peptide-AMC as ...
More data for this Ligand-Target Pair
Target Info
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MMDB
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KEGG
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Target
Histone deacetylase 11
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of N-terminal FLAG-tagged full length human HDAC11 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate incubated...
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Target Info
NCI pathway
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Target
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...
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Target Info
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Target
Histone deacetylase 4
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal GST-tagged/C-terminal His-tagged human HDAC4 (627 to 1084 residues) expressed in baculovirus expression system using Ac-pept...
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Target Info
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Target
Histone deacetylase 5
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal GST-tagged full length human HDAC5 (627 to 1084 residues) expressed in baculovirus expression system using Ac-peptide-AMC as...
More data for this Ligand-Target Pair
Target Info
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Target
Histone deacetylase 7
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal GST-tagged full length human HDAC7 (518 to end residues) expressed in baculovirus expression system using Ac-peptide-AMC as ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Histone deacetylase 9
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of C-terminal GST-tagged full length human HDAC9 (604 to 1066 residues) expressed in baculovirus expression system using Ac-peptide-AMC as...
More data for this Ligand-Target Pair
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Target
Polyamine deacetylase HDAC10
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of N-terminal FLAG-tagged full length human HDAC10 (2 to 631 residues) expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as...
More data for this Ligand-Target Pair
Target Info
NCI pathway
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Target
Histone deacetylase 2
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human HDAC2 using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Histone deacetylase 1
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Histone deacetylase 6
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Cytochrome P450 1A2
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: 1.68E+4nM
Assay Description:
Inhibition of CYP1A2 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Cytochrome P450 2E1
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: 6.92E+4nM
Assay Description:
Inhibition of CYP2E1 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: 9.28E+4nM
Assay Description:
Inhibition of CYP3A4 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS an...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
West China Hospital Of Sichuan University
Curated by
ChEMBL
Ligand
BDBM50579542
(CHEMBL4878408)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
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PC cid
PC sid
In Depth
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Article
PubMed
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