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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Glycogen synthase kinase-3 alpha
(Homo sapiens (Human))
University Of North Carolina
Curated by
ChEMBL
Ligand
BDBM50550133
(CHEMBL4754518)
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Affinity Data
IC50: 4.50E+3nM
Assay Description:
Inhibition of recombinant human GSK3alpha S449A mutant (2 to end residues) using YRRAAVPPSPSLSR peptide as substrate incubated for 40 mins in presenc...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
University Of North Carolina
Curated by
ChEMBL
Ligand
BDBM50550133
(CHEMBL4754518)
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Affinity Data
IC50: 5.10E+3nM
Assay Description:
Inhibition of full length recombinant human MAPK10 using peptide substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric scintill...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
Jinan University
Curated by
ChEMBL
Ligand
BDBM50550133
(CHEMBL4754518)
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Affinity Data
IC50: 6.60E+3nM
Assay Description:
Displacement of fluorescent tracer K5 from N-terminal full-length NanoLuc-fused RIOK2 (unknown origin) expressed in HEK293 cells using NanoGlo substr...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
PubMed
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Target
Serine/threonine-protein kinase RIO2
(Homo sapiens (Human))
Jinan University
Curated by
ChEMBL
Ligand
BDBM50550133
(CHEMBL4754518)
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Affinity Data
IC50: 6.60E+3nM
Assay Description:
Displacement of tracer K5 from N-terminal nanoluciferase-tagged RIOK2 (unknown origin) expressed in HEK293 cells measured after 2 hrs by NanoBRET ass...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
University Of North Carolina
Curated by
ChEMBL
Ligand
BDBM50550133
(CHEMBL4754518)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of full length recombinant human MAPK8 using ATF2 as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric scintilla...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
SNF-related serine/threonine-protein kinase
(Homo sapiens (Human))
University Of North Carolina
Curated by
ChEMBL
Ligand
BDBM50550133
(CHEMBL4754518)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of recombinant human SNRK E97G/P116A mutant (1 to 505 residues) using KKLRRTLSFAEPG peptide as substrate incubated for 40 mins in presence...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Homeodomain-interacting protein kinase 1
(Homo sapiens (Human))
University Of North Carolina
Curated by
ChEMBL
Ligand
BDBM50550133
(CHEMBL4754518)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human HIPK1 (158 to 555 residues) using myelin ba as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric scinti...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI