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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 17 hits in this display   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  1.60nMAssay Description:The compound was tested for binding affinity against human Dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  3.60nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 1A receptor receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  13.2nMAssay Description:The compound was tested for binding affinity against human Dopamine receptor D2LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  22nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor from rat brain using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  27nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  44nMAssay Description:Binding affinity of the compound to the dopamine receptor D2L in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  58nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi:  70.9nMAssay Description:The compound was tested for binding affinity against Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >500nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >500nMAssay Description:The compound was tested for binding affinity against alpha-2D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >500nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Sus scrofa)
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was tested for binding affinity against human Dopamine receptor D5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Sus scrofa)
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(RAT)
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was tested for binding affinity against H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Knoll Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50079939((7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)...)
Affinity DataKi: >1.00E+3nMAssay Description:The compound was tested for binding affinity against human Dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed