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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
70
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Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 0.260nM
Assay Description:
Displacement of [125]HEAT from human adrenergic alpha1a receptor expressed in CHO cells
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 0.300nM
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Target
Alpha-1D adrenergic receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.300nM
Assay Description:
Displacement of [125]HEAT from human adrenergic alpha1d receptor expressed in CHO cells
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.550nM
Assay Description:
Ability of the compound to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
In vitro binding affinity for 5-hydroxytryptamine 1A receptor in rat hippocampal membranes by [125I]-labeled agonist displacement.
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 1A receptor using 0.1 nM [3H]-8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)tet-ralin), from rat hippocampal ...
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Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 0.600nM
Assay Description:
Displacement of [3H]5-HT from human 5HT7 receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometry
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
In vitro ability to displace the radioligand [3H]-OH-DPAT from binding to rat 5-hydroxytryptamine 1A receptor
Checked by Author
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Binding affinity at 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes by [3H]-8-OH-DPAT displacement.
More data for this Ligand-Target Pair
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Inhibition of binding of [125I]8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenates
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
In vitro binding affinity to 5-hydroxytryptamine 1A receptor using [125I](R)-(+)-trans-8-OH-PIPAT as radioligand in rat hippocampal homogenate
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Binding affinity at 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes by [3H]8-OH-DPAT displacement.
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells after 120 mins
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPAT
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Binding affinity of compound towards 5-hydroxytryptamine 1A receptor in rat striatal membranes by [3H]-OH-DPAT displacement.
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brain
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Displacement of [3H]-8-OH-DPAT from rat hippocampus 5-HT1A receptor by liquid scintillation counting analysis
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.600nM
Assay Description:
Binding affinity towards 5-hydroxytryptamine 1A receptor of rat hippocampus using [3H]-8-hydroxy-2-(di-n-propylamine) tetralin (8-OH-DPAT) as a radio...
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.603nM
Assay Description:
Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacement
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.700nM
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Target
Alpha-1A adrenergic receptor
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.700nM
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 0.800nM
Assay Description:
Alpha-1 adrenergic receptor binding affinity of the compound, value taken from literature
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.800nM
Assay Description:
Binding affinity towards alpha-1 adrenergic receptor of rat frontal cortex using [3H]- WB- 4101 as a radioligand
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.800nM
Assay Description:
Binding affinity at Alpha-1 adrenergic receptor in rat cerebral cortex membranes by [3H]prazosin displacement.
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Target
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat))
Universit£
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.800nM
Assay Description:
Ability to displace beta ([125I]-iodo-4-hydroxyphenyl)-ethylaminomethyl tetralone from human Alpha-1a adrenergic receptor stably expressed in Chinese...
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Target
Alpha-1B adrenergic receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 0.960nM
Assay Description:
Displacement of [125]HEAT from human adrenergic alpha1b receptor expressed in CHO cells
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 1.25nM
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.26nM
Assay Description:
In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.
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Target
5-hydroxytryptamine receptor 1A
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 1.30nM
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Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 2nM
Assay Description:
Binding constant measured against Alpha-1A adrenergic receptor in human prostate; ++:moderately active
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 3nM
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 3.40nM
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 4.5nM
Assay Description:
Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells assessed as inhibitory constant incubated for 60 mins by radioligand...
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Target
D(3) dopamine receptor
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 9.30nM
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Target
D(2) dopamine receptor
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 14nM
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 38nM
Assay Description:
Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cells
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 47nM
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 50nM
Assay Description:
Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cells
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Universidad Complutense
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 64nM
Assay Description:
Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.
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Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Universidad Complutense
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 64nM
Assay Description:
Compound was evaluated for binding affinity against Dopamine receptor D2 using [3H]-raclopride as a radioligand
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 79.1nM
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 79.4nM
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 87nM
Assay Description:
Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor transfected in CFO-K1 cells after 30 mins by liquid scintillation spectrometry
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 87nM
Assay Description:
In vitro ability to displace the radioligand [3H]-5-CT from binding to rat 5-hydroxytryptamine 7 receptor
Checked by Author
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Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 87nM
Assay Description:
Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells incubated for 1 hr by microbeta plate reader analysis
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Target
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 203nM
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Target
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 204nM
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Target
5-hydroxytryptamine receptor 2A
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 219nM
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Target
5-hydroxytryptamine receptor 3A
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 316nM
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5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 549nM
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Target
5-hydroxytryptamine receptor 1B
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 617nM
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Target
5-hydroxytryptamine receptor 2C isoform A
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 630nM
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 646nM
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Target
5-hydroxytryptamine receptor 2C
(PIG)
Institut De Recherches Servier
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 776nM
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Target
5-hydroxytryptamine receptor 1D
(pigeon)
Cns-Pharmacology
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Ki: 794nM
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 1.00E+3nM
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 1.00E+3nM
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 1.00E+3nM
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Target
5-hydroxytryptamine receptor 7
(Rattus norvegicus (rat))
The Scripps Research Institute
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 1.00E+3nM
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5-hydroxytryptamine receptor 3A
(RAT)
Institut De Recherches Servier
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 1.00E+3nM
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Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Institut De Recherches Servier
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 1.07E+3nM
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Target
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat))
Institut De Recherches Servier
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
Ki: 1.07E+3nM
Assay Description:
Binding affinity at 5-hydroxytryptamine 1B receptor
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Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 4.12E+3nM
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Target
D(1A) dopamine receptor
(Homo sapiens (Human))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: 4.51E+3nM
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Target
5-hydroxytryptamine receptor 3A
(Mus musculus (house mouse))
Sri International
Curated by
PDSP K
i
Database
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
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Affinity Data
Ki: >1.00E+4nM
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
IC50: 1.10nM
Assay Description:
Antagonist activity at human recombinant 5-HT1A receptor expressed in CHOK1 cells incubated for 25 mins followed by addition of methiothepin by micro...
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
IC50: 1.10nM
Assay Description:
Antagonist activity at human recombinant 5-HT1A receptor expressed in CHOK1 cells incubated for 25 mins followed by addition of methiothepin by micro...
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
IC50: 4.70nM
Assay Description:
Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells co-expressing Galpha16 assessed as decrease in serotonin calcium mobilization ...
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Universita Degli Studi Di Bari
Curated by
ChEMBL
Ligand
BDBM82517
(2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...)
Copy SMILES
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Affinity Data
IC50: 5nM
Assay Description:
Antagonist activity at human 5-HT1A receptor expressed in CHO-K1 cells assessed as inhibition of serotonin-induced calcium mobilization preincubated ...
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