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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Histamine H3 receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
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Affinity Data
Ki: 0.0938nM
Assay Description:
Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histamine H3 receptor
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
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Affinity Data
IC50: 0.310nM
Assay Description:
Inverse agonist activity at human histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine-induced [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histamine H2 receptor
(Homo sapiens (Human))
Tsukuba Research Institute
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human histamine H2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Histamine H4 receptor
(Homo sapiens (Human))
Tsukuba Research Institute
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human histamine H4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Tsukuba Research Institute
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of [3H]prazosin from human adrenergic alpha1A receptor expressed in LMtk- cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Bioprojet-Biotech
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Displacement of [35S]MK499 from human ERG expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Histamine H1 receptor
(Homo sapiens (Human))
Tsukuba Research Institute
Curated by
ChEMBL
Ligand
BDBM50246435
(2-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-8-meth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human histamine H1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI