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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
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Target
Prostaglandin G/H synthase 1
(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: 130nM
Assay Description:
Inhibition of COX1
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Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: 150nM
Assay Description:
Inhibition of COX2
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Target Info
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Target
Prostaglandin G/H synthase 2
(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: 1.31E+4nM
Assay Description:
Anti-oxidant activity in DPPH radical scavenging assay; n=3-4
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Target Info
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KEGG
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Target
Acetylcholinesterase
(Homo sapiens (Human))
University Hospital Hradec Kralove
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: 1.86E+5nM
Assay Description:
Inhibition of human recombinant AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 min...
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Target
Polyphenol oxidase 2
(Agaricus bisporus (Common mushroom))
Kyung Hee University Skin Biotechnology Center
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of mushroom tyrosinase activity using L-tyrosin as substrate after 20 mins
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Target
Xanthine dehydrogenase/oxidase
(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of Xanthine oxidase
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Target Info
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Target
Dehydrogenase/reductase SDR family member 9
(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of 3alphaHSD
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Target
Cholinesterase
(Homo sapiens (Human))
University Hospital Hradec Kralove
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human plasmatic BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition measured every 2 mins...
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Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
University Hospital Hradec Kralove
Curated by
ChEMBL
Ligand
BDBM50359629
(TROLOX)
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Affinity Data
IC50: 4.00E+6nM
pH: 8.0
Assay Description:
AChE enzymatic activity was measured using an adaptation of the method previously described [Ingkaninan et al., J. Ethnopharmacol., 89:261-264]; 98 &...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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PC cid
PC sid
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In Depth
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Article
PubMed
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